SARS-CoV-2 infection during pregnancy and the risk of adverse maternal outcomes in the Republic of Georgia: a national birth registry-based cohort study

Table 2 Unadjusted and aORs and 95% CIs for the association between SARS-CoV-2 infection during pregnancy and maternal death, post-delivery intensive care unit admission, and caesarean section delivery

	No confirmed SARS-CoV-2 infection (reference group) n = 94,778		Confirmed SARS-CoV-2 infection in early pregnancy* n = 13,800			Confirmed SARS-CoV-2 infection within 30 days before or at delivery n = 2,915
Outcome	n	OR/aOR	n	OR (95%CI)	aOR (95%CI)	n	OR (95%CI)	aOR (95%CI)
Maternal death^a	16	1.0/1.0	1	0.43 (0.06–3.24)	0.47 (0.06–3.59)	22	45.03 (23.62–85.84)	43.11 (21.99–84.55)
Post-delivery intensive care unit admission^b	509	1.0/1.0	65	0.88 (0.68–1.14	0.93 (0.71–1.21)	75	4.89 (3.83–6.25)	5.20 (4.05–6.67)
Caesarean section delivery^c	39,720	1.0/1.0	6,182	1.12 (1.09–1.17)	1.07 (1.03–1.11)	1,337	1.17 (1.09–1.26)	1.11 (1.03–1.20)

aOR – adjusted odds ratio; 95% CI – 95% confidence interval; SARS-CoV-2 – severe acute respiratory syndrome coronavirus 2.
^aThe aOR was adjusted for age, education, parity, body mass index at first antenatal care visit, gestational diabetes, and COVID-19 vaccination.
^bThe aOR was adjusted for age, body mass index at first antenatal care visit, gestational diabetes, and COVID-19 vaccination.
^cThe aOR was adjusted for age, education, parity, body mass index at first antenatal care visit, gestational diabetes, and COVID-19 vaccination.
^*From conception until 31 days before delivery.

ISSN: 1471-2393