Skip to main content

Attention to pulmonary arteriovenous fistula in a case of transient hypoxemia and cerebral infarction during pregnancy: a case report and literature review

A Correction to this article was published on 21 September 2023

This article has been updated



Pulmonary arteriovenous fistula is rare during pregnancy. Pulmonary arteriovenous fistula presents no pulmonary symptoms in most patients but can be exacerbated by pregnancy. If not diagnosed and treated promptly, pulmonary arteriovenous fistula can lead to respiratory failure, stroke, spontaneous hemothorax, or other fatal complications.

Case presentation

A 29-year-old healthy pregnant woman presented with a transient drop in blood oxygen level of unknown cause during a routine examination at 34 weeks of gestation and during a cesarean section at 38 weeks of pregnancy. The patient’s oxygen saturation quickly returned to normal and was not further investigated. On day 3 postpartum, the patient suddenly displayed slurred speech and right limb myasthenia. A head magnetic resonance imaging revealed cerebral infarction in the left basal ganglia. Subsequent computed tomography pulmonary arteriography revealed bilateral pulmonary arteriovenous fistula, which was likely the cause of cerebral infarction. The patient was transferred to the Department of Thoracic Surgery after one month of treatment and successfully underwent percutaneous embolization of pulmonary arteriovenous fistula.


Pulmonary arteriovenous fistula should not be neglected if a pregnant woman presents with transient hypoxemia and cerebral infarction. A transient decrease in pulse oxygen saturation that cannot be explained by common clinical causes can be an early warning sign of the disease. Early diagnosis and multidisciplinary management could improve the prognosis.

Peer Review reports


Pulmonary arteriovenous fistula (PAVF) is a rare pulmonary vascular malformation that allows direct communication between the pulmonary artery and vein, bypassing the capillaries [1]. PAVF is mainly congenital but can be acquired in some cases, such as in patients with cirrhosis or those undergoing surgery for congenital heart disease. PAVF has been reported in 0.02‒0.03% of the population, primarily in women, and has a mortality rate of up to 11% [2]. Approximately 70% of PAVF cases are identified in patients with hereditary hemorrhagic telangiectasia (HHT), while the remaining 30% are sporadic cases unrelated to HHT [3]. Although PAVF has rarely been reported during pregnancy, medical screening in recent years has revealed a ≥ 0.38% PAVF incidence in the general asymptomatic population [4]. Therefore, more PAVF cases may be encountered during pregnancy.

Pregnancy has been reported to be a risk factor for the exacerbation of PAVF symptoms [5, 6]. PAVF patients often lack typical clinical presentations during pregnancy and are usually diagnosed upon the development of severe respiratory or neurological complications, including massive hemoptysis, hemothorax, and ischemic stroke. The mortality rate of PAVF is 1% in pregnant patients with good prenatal assessment [7]. Therefore, early diagnosis and management are critical for improving the prognosis of PAVF patients. The present study reports a rare case of gestational PAVF presented with transient hypoxemia and cerebral infarction. In addition, a literature review of PAVF during pregnancy is presented to provide a reference for the diagnosis and management of these patients.

Case presentation

A 29-year-old G2P1 pregnant woman at 34 weeks’ gestation was diagnosed with stable placenta accreta during a routine examination at the obstetric outpatient clinic of West China Second University Hospital, Sichuan University. The patient experienced dyspnea as she walked from the second floor to the outpatient clinic. Her pulse oximetry revealed an oxygen saturation level of 90%, which fluctuated between 90% and 95% during continued monitoring. After about 15 min of rest without oxygen inhalation, the patient experienced resolution of dyspnea, and her oxygen saturation level returned to 99%. The patient complained of progressively worsening dyspnea in the past month, which resolved spontaneously after resting without head elevation. The patient did not experience coughing, hemoptysis, nocturnal dyspnea, or other discomfort. Cardiopulmonary auscultation was unremarkable. The patient had a cesarean Sect. 3 years ago and had no underlying illnesses such as hypertension and diabetes. The patient’s physical examination was normal; thus, no further examinations or treatments were provided.

The patient was admitted to the Obstetrics Department of our hospital at 38 weeks of gestation for a cesarean section. After routine post-admission examinations, the patient underwent bilateral internal iliac artery balloon placement, followed by cesarean section under spinal-epidural anesthesia. The patient was slightly nervous before surgery but had normal vital signs and oxygen saturation. Epidural anesthesia (from T6 to S5) was successfully administered. One live infant was delivered successfully with clear amniotic fluid. However, the patient’s oxygen saturation gradually declined to 89% after delivery, which increased to 100% after administering 2 L/min of oxygen via a nasal cannula. The patient had no chest tightness, chest pain, shortness of breath, coughs, or remarkable fluctuations in heart rate and blood pressure. Auscultation revealed clear breath sounds without dry or wet rales and normal heart sounds. Skin mucosa was unremarkable. After the complete removal of the placenta and membranes, the patient exhibited poor uterine contraction and ruptured blood vessels in the lower uterine segment, resulting in substantial hemorrhage. Uterine massage and intramuscular injection of carboprost tromethamine were immediately provided to enhance uterine contraction. Emergency arterial blood gas analysis showed a PaO2 of 50 mmHg and Hb of 105 g/L with normal electrolytes. The uterine contraction improved and the bleeding was under control quickly. Coagulation, N-terminal brain natriuretic peptide level, and troponin level were unremarkable. D-dimer was 1.81 mg/L. Bedside electrocardiograph, echocardiogram, and vascular ultrasound of the lower extremities were normal. There were no drastic fluctuations in the patient’s heart rate, blood pressure, and respiration during the cesarean section. The operation lasted approximately 1.5 h with an estimated blood loss of 1000 mL. No blood transfusion was required.

The patient was transferred to the intensive care unit after surgery and had an oxygen saturation level of 99% with oxygen administration (2 L/min by nasal cannula). On day 1, after surgery, the patient was conscious without discomfort. Without oxygen administration, she had a 97% oxygen saturation level and began ambulatory activities. On day 3, after surgery, the patient exhibited slurred speech during ambulation, accompanied by right limb myasthenia. An emergency head magnetic resonance imaging revealed cerebral infarction in the left basal ganglia. The patient was subsequently referred for chest and abdominal computed tomography angiography, heart ultrasound, and transcranial Doppler ultrasound to identify the underlying cause of these symptoms. Computed tomography pulmonary arteriography (CTPA) revealed bilateral multiple pulmonary vascular malformations (Fig. 1). The patient’s symptoms significantly improved after antiplatelet and anticoagulant therapy. After one month of treatment, the patient was conscious and articulate, with normal muscle strength in her right limb. She was then transferred to the Department of Thoracic Surgery for percutaneous embolization of PAVF. During the telephone follow-up 6 months after surgery, the patient reported no discomfort or adverse impacts on her quality of life. Her child was also healthy.

Fig. 1
figure 1

CTPA demonstrates multiple vascular malformations in both lungs. A In the anterior segment of the superior lobe of the right lung, the thickened right superior pulmonary artery is the feeding artery, and the right superior pulmonary vein is the drainage vein, with apparent signs of PAVF. B In the posterior basal segment of the lower lobe of the left lung, signs of PAVF are observed


PAVF in pregnancy is a rare and potentially fatal condition with limited experience in its identification and management. In this case study, the patient suffered a cerebral infarction three days after giving birth. She was diagnosed with PAVF, which might be the cause of cerebral infarction. Gestational conditions, postpartum hemorrhage, dilated and tortuous vessels near the arteriovenous fistula and poor circulation further increase the risk of thrombosis in PAVF patients [8]. Despite the active postoperative application of lower extremity pneumatic pump therapy and anticoagulant to prevent venous thrombosis, the patient still developed thrombosis. Furthermore, the thrombus flowed into pulmonary vein through a fistula and circulated to the cerebral vessels leading to the occurrence of cerebral infarction. A transient decrease in pulse oxygen saturation of unknown causes was the only clinical presentation of the patient in the late stage of pregnancy and after delivery, possibly as a result of the significant increase in blood flow through the right-to-left shunt in the lungs due to rapid changes in hemodynamics [6]. With the regulation of the distribution of blood circulation system, the right-to-left shunt decreased, and the oxygen saturation returned to normal.

Our case highlights the following main points. PAVF should not be neglected in pregnant women with transient hypoxemia and cerebral infarction. A transient decrease in pulse oxygen saturation that cannot be explained by common clinical causes might be an early warning sign of this medical condition.

Most patients show no typical symptoms, making early identification difficult [9]. We searched the Web of Science and PubMed databases without language restriction to identify case reports or case series published up to 30 June 2023 using the following terms: “pulmonary arteriovenous fistula or pulmonary arteriovenous malformation” and “pregnancy.” Twenty-nine cases of PAVF diagnosed during pregnancy were retrieved [3, 6, 10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36]. The patients’ characteristics and treatments are presented in Table 1. The gestational age of the pregnant patients in these case reports ranged from 7 to 39 weeks. There were 27 cases of PAVF in the second and third trimester. There were 20 cases with complications as the initial presentation, including 20 cases of hemothorax, and one case of cerebral infarction and deep venous thrombosis. One patient died due to severe respiratory failure. Dyspnea or hypoxemia was the most prominent early presentation in the remaining 9 cases who had no complications during pregnancy, consistent with that in general PAVF patients [37]. However, dyspnea, a non-specific complaint during the second and third trimester, is a common symptom of pregnancy, thus making it difficult to diagnose [18]. In contrast, hypoxemia may help in early identification of PAVF. The recurrent transient drop in oxygen saturation may be one of the clinical manifestations in pregnant women with PAVF and should therefore be closely monitored [38].

Table 1 29 cases of PAVF diagnosed during pregnancy before 2023

Arterial blood gas analysis remains ideal to detect hypoxemia. If oxygen desaturation cannot be explained by common causes, PAVF should be considered as it is the most common cause of hypoxemia induced by extracardiac shunt. Large PAVF can generally be identified by plain or contrast-enhanced computed tomography scans [39]. Once identified, transthoracic contrast echocardiography can be performed to further examine the fistula [40]. Chest magnetic resonance imaging can also be a safer alternative for the fetus. CTPA or pulmonary arteriography can clearly show the site of PAVF and the number of supplying arteries. CTPA is the preferred diagnostic angiography approach due to its non-invasiveness. Once PAVF is confirmed, the physician should exclude HHT and assess whether vascular malformations exist at other sites, such as the heart, liver, and brain [41], because some patients may have HHT [7]. In our case, the patient had no history of frequent nasal bleeding, no personal or family history of telangiectasia, and no vascular malformations in other sites and was thus unlikely to be comorbid with HHT. Genetic testing was recommended to the patient for a definite diagnosis, but she refused due to financial constraints.

Currently, treatments for PAVF are decided based on clinical judgments, case reports in the literature, and consultations in a multidisciplinary team [35]. It has been reported that treatments should always be provided to patients with PAVF before pregnancy, regardless of the presence or absence of clinical symptoms, to avoid the development of potentially fatal complications during pregnancy [42]. For those with proper cardiopulmonary function, regular arterial blood gas monitoring and chest x-ray or computed tomography examinations should be performed to evaluate the progression of PAVF. Furthermore, doctors should carry out a dynamic assessment of thrombotic risk factors and take steps to prevent thrombosis [7]. PAVF patients are prone to severe complications during the second and third trimesters of pregnancy, childbirth, and the early postpartum period. Therefore, monitoring during these periods needs to be intensified. The approaches for delivery and anesthesia should be individualized. The endovascular technique of embolization has been recently accepted worldwide as mainstay of treatment and should be performed at time of diagnosis or when the following criteria are satisfied: progressive enlargement of a detected PAVF, symptomatic hypoxemia, or serious complications [43]. It is safe and effective after 16 weeks of gestation [6, 44]. Surgery during pregnancy poses a significant clinical challenge as it can lead to atelectasis, pulmonary edema, and premature birth. The effect of pregnancy on PAVF recanalization is currently unclear, and postpartum patients should undergo long-term follow-ups [45].


This case emphasizes that PAVF should be suspected if a pregnant patient presents with transient hypoxemia and cerebral infarction. And a transient decrease in pulse oxygen saturation that cannot be explained by common clinical causes can be an early indication of this disease. The physician should be alert to complications of pulmonary arteriovenous fistula during pregnancy. Early diagnosis and multidisciplinary management could improve the prognosis.

Data Availability

The data sets used and analyzed during the current study are available from the corresponding author upon reasonable request.

Change history



Pulmonary arteriovenous fistula


Computed tomography pulmonary arteriography


Hereditary hemorrhagic telangiectasia


  1. Graves AD, Gregorius JC, Smith DC. Management of a patient with a clot-filled pulmonary arteriovenous malformation. J Vasc Interv Radiol. 2009;5(20):652–5.

    Google Scholar 

  2. Shovlin CL, Condliffe R, Donaldson JW, Kiely DG, Wort SJ. British thoracic society clinical statement on pulmonary arteriovenous malformations. Thorax. 2017;12(72):1154–63.

    Google Scholar 

  3. Liu S, Zhang Q, Liu W, Zheng L, Zhou J, Huang X. Hereditary haemorrhagic telangiectasia with atrial septal defect and pulmonary hypertension during advanced pregnancy: a case report and literature review. J Int Med Res. 2022;50(4):1–8.

    Google Scholar 

  4. Nakayama M, Nawa T, Chonan T, Endo K, Morikawa S, Bando M, et al. Prevalence of pulmonary arteriovenous malformations as estimated by low-dose thoracic CT screening. Intern Med. 2012;51(13):1677–81.

    PubMed  Google Scholar 

  5. Tellapuri S, Park HS, Kalva SP. Pulmonary arteriovenous malformations. Int J Cardiovasc Imaging. 2019;35(8):1421–8.

    PubMed  Google Scholar 

  6. Gershon AS, Faughnan ME, Chon KS, Pugash RA, Clark JA, Bohan MJ, et al. Transcatheter embolotherapy of maternal pulmonary arteriovenous malformations during pregnancy. Chest. 2001;119(2):470–7.

    CAS  PubMed  Google Scholar 

  7. Shovlin CL, Sodhi V, McCarthy A, Lasjaunias P, Jackson JE, Sheppard MN. Estimates of maternal risks of pregnancy for women with hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome): suggested approach for obstetric services. BJOG. 2008;9(115):1108–15.

    Google Scholar 

  8. Cha JG, Hong J. Concurrent pulmonary arteriovenous malformation and pulmonary embolism causing stroke: a therapeutic dilemma. CVIR Endovasc. 2022;5(1):4.

    PubMed  PubMed Central  Google Scholar 

  9. Keinath K, Vaughn M, Cole N, Gentry S. Exertional hypoxia in a healthy adult: a pulmonary arteriovenous malformation. BMJ Case Reports. 2019;12(10):1–3.

    Google Scholar 

  10. Gammon RB, Miksa AK, Keller FS. Osler-Weber-Rendu disease and pulmonary arteriovenous fistulas. Deterioration and embolotherapy during pregnancy. Chest. 1990;98(6):1522–4.

    CAS  PubMed  Google Scholar 

  11. Chanatry BJ. Acute hemothorax owing to pulmonary arteriovenous malformation in pregnancy. Anesth Analg. 1992;74(4):613–5.

    CAS  PubMed  Google Scholar 

  12. Laroche CM, Wells F, Shneerson J. Massive hemothorax due to enlarging arteriovenous fistula in pregnancy. Chest. 1992;101(5):1452–4.

    CAS  PubMed  Google Scholar 

  13. Bevelaqua FA, Ordorica SA, Lefleur R, Young B. Osler-Weber-Rendu disease. Diagnosis and management of spontaneous hemothorax during pregnancy. N Y State J Med. 1992;92(12):551–2.

    CAS  PubMed  Google Scholar 

  14. Baumgardner DJ, Kroll MR. Pulmonary arteriovenous malformation in pregnancy. Am Fam Physician. 1993;48:10332.

    Google Scholar 

  15. Shovlin CL, Winstock AR, Peters AM, Jackson JE, Hughes JM. Medical complications of pregnancy in hereditary hemorrhagic telangiectasia. Q J Med. 1995;88:879–87.

    CAS  Google Scholar 

  16. Wilmshurst P, Jackson P. Arterial hypoxemia during pregnancy caused by pulmonary arteriovenous Microfi. Chest. 1996;110(5):1368–9.

    CAS  PubMed  Google Scholar 

  17. Adegboyega PA, Yuoh G, Adesokan A. Recurrent massive emothorax in Rendu-0sler-Weber syndrome. South Med J. 1996;89:1193–6.

    CAS  PubMed  Google Scholar 

  18. Esplin MS, Varner MW. Progression of pulmonary arteriovenous malfomation during pregnancy: case report and review of the literature. Obstet Gynecol Surv. 1997;52:248–53.

    CAS  PubMed  Google Scholar 

  19. Lee BH. Young Seon Cho. A case of multiple pulmonary arteriovenous malformations in pregnancy. Tuberc Respir Dis. 2002;52:545–9.

    Google Scholar 

  20. Wong AS, Cheung GW, Manlulu AV, Wan I, Chu MC, Yu SCh, et al. Ruptured pulmonary arteriovenous malformation during pregnancy. Acta Obstet Gynecol Scand. 2006;85(10):1273–5.

    CAS  PubMed  Google Scholar 

  21. Zhao Y, Li GY, Yang Z, Zhang P, Zhang K, Shao G. Bilateral heterochronic spontaneous hemothorax caused by pulmonary arteriovenous malformation in a gravid: a case report. J Cardiothorac Surg. 2010;5(31):96.

    PubMed  PubMed Central  Google Scholar 

  22. Anin SR, Ogunnoiki W, Sabharwal T, Harrison-Phipps K. Pulmonary arteriovenous malformation unmasked in pregnancy: a case report. Obstet Med. 2013;6(4):179–81.

    PubMed  PubMed Central  Google Scholar 

  23. Di Crescenzo V, Napolitano F, Vatrella A, Zeppa P, Laperuta P. Pulmonary arterovenous malformation causing hemothorax in a pregnant woman without Osler-Weber-Rendu syndrome. Open Med (Wars). 2015;10(1):549–54.

    PubMed  Google Scholar 

  24. Raiya S, Athavale A, Nair J, Deshmukh H. Hereditary hemorrhagic telangiectasia with hemothorax in pregnancy. Lung India. 2017;34:206–7.

    PubMed  PubMed Central  Google Scholar 

  25. Tajima H, Kasai H, Sugiura T, Tatsumi K. Pulmonary arteriovenous fistula complicated by venous thromboembolism and paradoxical cerebral infarction during early pregnancy. BMJ Case Rep. 2018;6:1–3.

    Google Scholar 

  26. Texier C, Accoceberry M, Grobost V, Chadeyras JB, Gallot D. Osler-Weber-Rendu disease diagnosed during pregnancy because of an important hemothorax. Gynecol Obstet Fertil Senol. 2018;46:668–70.

    CAS  PubMed  Google Scholar 

  27. Md Noh MSF, Abdul Rashid AM, Abdul Rahim EA. Massive hemothorax in a pregnant woman: role of interventional radiology. J Bronchol Interv Pulmonol. 2018;25(3):e30–32.

    Google Scholar 

  28. Wang HC, Zhang JH, How CH. Emergency video-assisted thoracic surgery for ruptured pulmonary arteriovenous malformation-related hemothorax in a pregnant woman: a case report. J Med Case Rep. 2018;12(1):75.

    PubMed  PubMed Central  Google Scholar 

  29. Borovac-Pinheiro A, Cavichiolli FS, Costa ML, Surita FG. Osler-Weber-Rendu syndrome in pregnancy affecting lungs and brain-a case report. J Obstet Gynaecol. 2019;39(5):709–11.

    PubMed  Google Scholar 

  30. Klein M, Brandl R, Kundel C. Pulmonary arteriovenous malformation. Dtsch Arztebl Int. 2019;116(20):364.

    PubMed  PubMed Central  Google Scholar 

  31. Di Guardo F, Lo Presti V, Costanzo G, Zambrotta E, Di Gregorio LM, Basile A, et al. Pulmonary Arteriovenous Malformations (PAVMs) and pregnancy: a rare case of hemothorax and review of the literature. Case Rep Obstet Gynecol. 2019;2019:8165791.

    PubMed  PubMed Central  Google Scholar 

  32. Naito JNT, Morimoto J, Yamamoto T, Sakairi Y, Wada H, Suzuki H, Sugiura T, Tatsumi K, Yoshino I. Emergency surgery for hemothorax due to a ruptured pulmonary arteriovenous malformation. Gen Thorac Cardiovasc Surg. 2020;68(12):1528–31.

    PubMed  Google Scholar 

  33. Van den Bulck M, Berenger Ngah C, Ntula H, Gorur Y, Cardos B, Brisbois D, et al. Haemothorax in a pregnant woman secondary to rupture of a pulmonary arteriovenous malformation. Eur J Case Rep Intern Med. 2022;9(9):003549.

    PubMed  PubMed Central  Google Scholar 

  34. Zamaniyan M, Jafari K, Kargar-Soleimanabad S, Nikzad Jamnani A. Spontaneous hemothorax during pregnancy: a case report. Int J Surg Case Rep. 2022;99: 107660.

    PubMed  PubMed Central  Google Scholar 

  35. Lukic A, Cmelak L, Drazenovic D, Kojundzic H, Lukic IK, Gluncic V. Pulmonary arteriovenous malformation unmasked by pregnancy: a review of pulmonary arteriovenous malformations and cardiovascular and respiratory changes in Pregnancy. Case Rep Pulmonol. 2023;2023:5469592.

    PubMed  PubMed Central  Google Scholar 

  36. Robinson TJ, Anamah B, Winter WB, Imani-Shikhabadi R. Spontaneous hemothorax in pregnant patient with pulmonary arteriovenous malformation. Radiol Case Rep. 2023;18(2):679–84.

    PubMed  Google Scholar 

  37. Wilmhurst P, Jackson P. Arterial hypoxemia during pregnancy caused by pulmonary arteriovenous microfistulas. Chest. 1996;110:368–1369.

    Google Scholar 

  38. Veil-Picard M, Cattin J, Chopard R, Schiele F, Riethmuller D, Dalphin JC, et al. Hypoxaemia during pregnancy: pulmonary arteriovenous dilatation as a likely cause. Eur Respir Rev Eur Respir Rev. 2014;23(134):531–3.

    PubMed  Google Scholar 

  39. Vorselaars VMM, Velthuis S, Huitema MP, Hosman AE, Westermann CJJ, Snijder RJ, et al. Reproducibility of right-to-left shunt quantification using transthoracic contrast echocardiography in hereditary haemorrhagic telangiectasia. Neth Heart J. 2018;26(4):203–9.

    CAS  PubMed  PubMed Central  Google Scholar 

  40. Yn Z. Diagnosis and follow-up of pregnancy related pulmonary arteriovenous shunt by contrast echocardiography of right heart. Chin J Med Ultrasound. 2017;12(14):959–60.

    Google Scholar 

  41. Meek ME, Meek JC, Beheshti MV. Management of pulmonary arteriovenous malformations. Semin Interv Radiol. 2011;28:24–31.

    Google Scholar 

  42. Majumdar S, McWilliams JP. Approach to Pulmonary Arteriovenous Malformations: a Comprehensive Update. J Clin Med. 2020;9(6):1927.

    PubMed  PubMed Central  Google Scholar 

  43. Müller-Hülsbeck S, Marques L, Maleux G, Osuga K, Pelage JP, Wohlgemuth WA, et al. CIRSE Standards of practice on diagnosis and treatment of pulmonary arteriovenous malformations. Cardiovasc Intervent Radiol. 2020;3(43):353–61.

    Google Scholar 

  44. Andersen PE, Tørring PM, Duvnjak S, Gerke O, Nissen H, Kjeldsen AD. Pulmonary arteriovenous malformations: a radiological and clinical investigation of 136 patients with long-term follow-up. Clin Radiol. 2018;11(73):951–7.

    Google Scholar 

  45. Pick A, Deschamps C, Stanson AW. Pulmonary arteriovenous fistula: presentation, diagnosis, and treatment. World J Surg. 1999;11(23):1118–22.

    Google Scholar 

Download references


The researchers thank the Department of Obstetrics and Gynecology Intensive Care Unit, West China Second University Hospital, Sichuan University for their support during the data collection process.


No sources of funding exist for this research. All costs were covered by the researchers.

Author information

Authors and Affiliations



LS and LL designed the entire study, wrote the proposal, participated in the data collection, analyzed the data, and drafted the paper. YZ approved the proposal and revised the subsequent drafts of the paper. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Yunxia Zuo.

Ethics declarations

Ethics approval and consent to participate

Ethical permission was granted by the the Ethics Review Committee of the Second West China Hospital of Sichuan University in China. Written informed consent was obtained from the patient. All identifying information of the participant was kept confidential.

Consent for publication

Written informed consent was obtained from the patient to publish of this case report.

Competing interests

The authors have no relevant financial or nonfinancial interests to disclose.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The original online version of this article was revised: the authors reported an error in the affiliations. Affiliations 4 and 5 are need to be swapped.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Shu, L., Luo, L. & Zuo, Y. Attention to pulmonary arteriovenous fistula in a case of transient hypoxemia and cerebral infarction during pregnancy: a case report and literature review. BMC Pregnancy Childbirth 23, 626 (2023).

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: