Table 3 Association of pre-BMI and adverse pregnancy outcomes stratified by MTHFR A1298C dominant model

GDM

Normal weight

1 (ref)

1 (ref)

0.076

Underweight

0.59 (0.44–0.81) *

0.95 (0.65–1.34)

Overweight

1.70 (1.19–2.45) *

1.83 (1.15–2.79) *

Obesity

2.11 (1.20–3.73) *

2.00 (0.87–4.60)

GHT

Normal weight

1 (ref)

1 (ref)

0.201

Underweight

0.64 (0.40–1.01)

0.64 (0.34–1.21)

Overweight

2.53 (1.57–4.09) *

2.28 (1.22–4.27) *

Obesity

2.20 (1.01–4.82) *

6.49 (2.67–15.79) *

CS

Normal weight

1 (ref)

1 (ref)

0.073

Underweight

0.76 (0.61–0.96) *

0.52 (0.39–0.69) *

Overweight

1.64 (1.17–2.30) *

1.26 (0.84–1.81)

Obesity

2.23 (1.29–3.86) *

4.18 (1.75–9.99) *

PROM^#

Normal weight

1 (ref)

1 (ref)

0.045*

Underweight

0.93 (0.72–1.19)

0.87 (0.66–1.20)

Overweight

1.10 (0.75–1.61)

0.85 (0.51–1.39)

Obesity

0.67 (0.33–1.34)

0.60 (0.20–1.75)