Maternal pre-pregnancy BMI, MTHFR polymorphisms, and the risk of adverse pregnancy outcomes in pregnant women from South China: a retrospective cohort study

Table 2 Association between maternal pre-BMI categories and adverse pregnancy outcomes

Pregnancy outcomes	BMI status	Case/Control	OR (95% CI)	P
GDM	Normal weight	753/3259	1 (ref)
	Underweight	145/958	0.72 (0.57–0.90)	< 0.001
	Overweight	122/264	1.73 (1.31–2.29)	0.002
	Obesity	34/79	2.13 (1.33–3.41)	0.005
GHT	Normal weight	254/3758	1 (ref)
	Underweight	45/1058	0.68 (0.46–0.99)	0.047
	Overweight	54/332	2.54 (1.72–3.75)	0.000
	Obesity	19/94	3.53 (1.96–6.36)	0.000
CS	Normal weight	1505/2507	1 (ref)
	Underweight	290/813	0.66 (0.55–0.79)	< 0.001
	Overweight	192/194	1.47 (1.14–1.89)	0.003
	Obesity	62/51	2.64 (1.67–4.17)	< 0.001
PROM	Normal weight	989/3023	1 (ref)
	Underweight	260/843	0.92 (0.76–1.11)	0.36
	Overweight	89/297	0.99 (0.73–1.34)	0.99
	Obesity	16/97	0.65 (0.76–1.16)	0.92

GHT were adjusted for maternal age, education level, parity, gestational age at delivery, infant sex, and homocysteine
GDM, PROM, and CS were adjusted for maternal age, education level, parity, and homocysteine
GHT, gestational hypertension; GDM, gestational diabetes mellitus; CS, cesarean section; PROM, premature rupture of membranes

ISSN: 1471-2393