Fig. 1

Flower diagram, bar chart and taxonomic analysis. A Flower diagram showing the number of common and unique amplicon sequence variants (ASVs) among the eight subgroups. Different subgroups are represented by different colors. Petals indicate the ASVs unique to each subgroup. The core shows the common ASVs across the subgroups. B Bar chart showing a number of ASVs classified to the family, genus, and species levels. C-D Taxonomic analysis. AZ1, TPOAb⁺-LT₄⁻-T2, women in T2 with TPOAb-positive SCH and no LT₄ treatment; AW1, TPOAb⁺-LT₄⁻-T3, women in T3 with TPOAb-positive SCH and no LT₄ treatment; BZ1, TPOAb⁻-LT₄⁻-T2, women in T2 with TPOAb-negative SCH and no LT₄ treatment; BW1, TPOAb⁻-LT₄⁻-T3, women in T3 with TPOAb-negative SCH and no LT₄ treatment; AZ2, TPOAb⁺-LT₄⁺-T2, women in T2 with TPOAb-positive SCH and LT₄ treatment; AW2, TPOAb⁺-LT₄⁺-T3, women in T3 with TPOAb-positive SCH and LT₄ treatment; BZ2, TPOAb⁻-LT₄⁺-T2, women in T2 with TPOAb-negative SCH and LT₄ treatment; BW2, TPOAb⁻-LT₄⁺-T3, women in T3 with TPOAb-negative SCH and LT₄ treatment