Table 4 Species with significant correlations with the highest aMED Scores (> 6)
From: Adherence to Mediterranean diet impacts gastrointestinal microbial diversity throughout pregnancy
Genus_Species | Correlation (r) | p-value | Metabolic Production and Physiologic Effects cited in literature |
|---|---|---|---|
Lactobacillus_rogosae | 0.277 | 0.007 | Decreased in women with Gestational Diabetes [23] |
Coprococcus_eutactus | 0.256 | 0.012 | Actively ferments carbohydrates, produces butyric and acetic acids with formic or propionic and/or lactic acid [24] |
Phascolarctobacterium_faecium | 0.243 | 0.018 | Produces short-chain fatty acids, including acetate and propionate, upregulated by metformin in animal models [25] |
Anaerococcus_tetradius | 0.242 | 0.018 | Primarily found in vagina and female reproductive tract. Ferments glucose and mannose, butyrate is an end-product [26] |
Collinsella_aerofaciens | 0.235 | 0.022 | Unique collinsella species with butyrate kinase [27] |
Alistipes_sp. | 0.229 | 0.025 | Negative correlation with glucose intolerance in pregnancy [28] |
Faecalibacterium_prausnitzii | 0.205 | 0.046 | Butyrate producing, Anti-inflammatory properties, associated with low secretion of pro-inflammatory cytokines (IL-12 and IFN-γ), and elevated secretion of the anti-inflammatory cytokine IL-10 [36, 38, 39]. |
Pseudobutyrivibrio_ruminis | 0.202 | 0.050 | Butyrate producer [23] |