Skip to main content

Challenging the status quo: results of an acceptability and feasibility study of hypertensive disorders of pregnancy (HDP) management pathways in Indonesian primary care

Abstract

Background

Hypertensive disorders of pregnancy (HDP) are the leading cause of maternal mortality in Indonesia. Focused HDP management pathways for Indonesian primary care practice have been developed from a consensus development process. However, the acceptability and feasibility of the pathways in practice have not been explored. This study reports on the implementation process of the pathways to determine their acceptability and feasibility in Indonesian practice.

Methods

The pathways were implemented in three public primary care clinics (Puskesmas) in Yogyakarta province for a month, guided by implementation science frameworks of Medical Research Council (MRC) and the Practical Robust Implementation and Sustainability Model (PRISM). The participating providers (general practitioners (GPs), midwives, and nurses) were asked to use recommendations in the pathways for a month. The pathway implementation evaluations were then conducted using clinical audits and a triangulation of observations, focus groups (FGs), and interviews with all of the participants. Clinical audit data were analysed descriptively, and qualitative data were analysed using a mix of the inductive-deductive approach of thematic analysis.

Results

A total of 50 primary care providers, four obstetricians, a maternal division officer in the local health office and 61 patients agreed to participate, and 48 of the recruited participants participated in evaluation FGs or interviews. All of the providers in the Puskesmas attempted to apply recommendations from the pathways to various degrees, mainly adopting preeclampsia risk factor screenings and HDP monitoring. The participants expressed that the recommendations empowered their practice when it came to HDP management. However, their practices were challenged by professional boundaries and hierarchical barriers among health care professionals, limited clinical resources, and regulations from the local health office. Suggestions for future scale-up studies were also mentioned, such as involving champion obstetricians and providing more patient education toolkits.

Conclusion

The HDP management pathways are acceptable and feasible in Indonesian primary care. A further scale-up study is desired and can be initiated with investigations to minimise the implementation challenges and enhance the pathways’ value in primary care practice.

Peer Review reports

Background

Hypertensive disorders of pregnancy (HDP) are the second-highest cause of global maternal mortality [1]. Diagnosis criteria for HDP include ranges of hypertensive conditions in pregnancy, such as chronic hypertension, gestational hypertension, and preeclampsia. The disorders are experienced by up to 10% of pregnant women worldwide [1, 2], and related complications can lead to maternal deaths, which mostly occur in low- and middle-income countries (LMICs) [1, 3]. In Indonesia, HDP causes about a thousand maternal deaths each year and a high number of infant morbidity, as many women with HDP have to deliver their babies prematurely [4, 5].

Despite the significant impact on maternal mortality caused by HDP, unfortunately there are limited guidelines on HDP management available in Indonesian primary care [6]. The existing HDP guidelines in the setting only recommend general practitioners (GPs) to refer pregnant women to hospitals. However, more detailed on the screening, diagnostics, and HDP procedures before referrals are hardly mentioned [7, 8]. Therefore, it is not surprising that many women already present with severe HDP conditions at the hospitals, as many do not receive appropriate management in primary care, such as antihypertensive medications and the maintenance of adequate maternal and foetal wellbeing [9, 10].

This paper reports the final phase of a larger research project which aimed to develop HDP management pathways for Indonesian primary care [6]. Recommendations included in the HDP pathways were informed by results of a review of international HDP guidelines and preliminary interviews with Indonesian key stakeholders [11, 12]. The recommendations then went through a consensus development process using Delphi technique to explore the experts' agreement for the readiness of the recommendations to be used in Indonesian primary care settings [6, 13, 14]. The aim of this final phase was to determine the acceptability and feasibility of the pathways in Indonesian primary care practice. Specific objectives covered in this phase were to explore Indonesian primary care providers’ experience of using the pathways, including implementation barriers and facilitators for the pathways in practice settings.

Methods

Theoretical Frameworks

Two implementation science frameworks were used to guide the study. The first framework, the Medical Research Council (MRC) [15], guided the study stages to determine acceptability and feasibility of the pathways before their implementation in more extensive primary care settings [6]. The second framework, the Practical Robust Implementation and Sustainability Model (PRISM) [16], was used to guide the development of guiding questions in the implementation evaluation, as well as to guide selections of recipients of the pathways/participants in the study. According to PRISM, they were those who used or were impacted by the pathways, such as GPs, nurses, midwives, patients, obstetricians, and local health officers [6, 16].

Design

This study applied a mixed-methods design informed by MRC [15] and PRISM [16]. The pathway implementation was conducted from July–November 2019 and consisted of three implementation stages:

  • Stage 1 – Capacity building. Pre-implementation seminars were held at each Puskesmas to provide participants with information regarding the HDP pathways.

  • Stage 2 – Implementation. The developed HDP pathways were implemented in three Puskesmas for a month. The Puskesmas providers were asked to use and apply recommendations in the pathways in their routine antenatal care (ANC).

  • Stage 3 – Implementation evaluation. The evaluation was conducted following a one-month implementation using a triangulation approach of clinical audits, observations, focus groups (FGs), and interviews with primary care providers, as well as interviews with patients, obstetricians, and local health officers.

Study setting

This study took place in three Puskesmas in Bantul District, Yogyakarta Province, Indonesia. Puskesmas are government-mandated community primary health care clinics located across Indonesia that provide individual health consultations, surveillance and public health programs. They are the backbone of the Indonesian primary care service, ensuring the availability of the service across Indonesian provinces [17]. Yogyakarta itself has 121 Puskesmas and 27 of them are located in Bantul district [18]. Bantul was selected as the setting of the study for its high number of maternal mortality cases in 2019. From 36 maternal deaths in Yogyakarta, third of the cases were from Bantul and around a third of the total cases in Yogyakarta were caused by preeclampsia [18, 19].

Regarding the three Puskesmas: Puskesmas 1 is a satellite clinic located in a rural area in the district. Patients accessing Puskemas 1 tend to be of low socioeconomic status, and include workers such as farmers and labourers. Puskesmas 2 is located in a more metropolitan area, close to the provincial capital, and provides care to wealthier populations compared to Puskesmas 1. Puskesmas 3 is located in a rural coastal area and most of its patients are farmers or fishermen. Most antenatal care (ANC) procedures in the three Puskesmas are covered by Jaminan Kesehatan Nasional (JKN) as the Indonesian public insurance [20] or Jaminan Kesehatan Daerah (Jamkesda) as the local district-level insurance [21].

Interventions

The primary interventions implemented in the study were the developed HDP management pathways for Indonesian primary care [22]. They consisted of: (i) an HDP diagnosis flowchart (Fig. 1); (ii) an HDP management pathway (Fig. 2); and (iii) an HDP surveillance pathway (Fig. 3) [22]. The participants were then also provided with multifaceted intervention toolkits, such as:

  • Educational tools. Each Puskesmas received up to 20 training modules containing a detailed explanation of the HDP pathways and two HDP management pathways posters (see Fig. 2).

  • Reminder tools. Primary care provider participants received stickers, pens, andlanyards, and patient participants received mugs, notebooks, and stickers explaining essential information on HDP management.

  • A patient examination tool. Primary care provider participants received a checklist of high and moderate clinical preeclampsia risk-factors to enable a more practical patient screening in Puskesmas.

Fig. 1
figure1

HDP diagnosis flowchart [22]

Fig. 2
figure2

Hypertensive disorders of pregnancy (HDP) management pathway used in the study, developed from the consensus development process [22]

Fig. 3
figure3

Surveillance pathway for women with HDP in Indonesian primary care [22]

Recruitment

Puskesmas

The three participating Puskesmas were identified from the first author’s networks and were approached following an initial consultation with the maternal health division in the local health office. Formal invitations, including the plain language statement (PLS) and consent form, were also sent to head of each Puskesmas for their participation approval.

Clinicians and the health officer

Recruitment of the primary care providers, such as GPs, nurses, and midwives, was conducted face-to-face at each Puskesmas after obtaining research approval from the head of each Puskesmas. Obstetricians working within the Puskesmas’ networks and local health officers were invited to participate via phone, short message service (SMS) [23], and WhatsApp messenger [24]. All participants were provided with PLS and consent form of the study, and they had opportunities to ask questions before consenting.

Patients

Patient recruitment was conducted in waiting rooms in each Puskesmas. The women were asked politely whether they visited Puskesmas for their ANC and whether they were interested to participate in the study. They were provided with the study PLS and consent form, and were able to ask any questions before consenting. They were also informed that they might receive different treatments, medications, or tests compared to their usual care, and that their ANC consultations may be observed and recorded. At the end of the implementation period, women who attended a minimum of two ANC visits in the Puskesmas were invited to participate in the evaluation interviews.

Data collection

The data collection for the pathway implementation evaluation consisted of clinical audits, observations of GP/midwife-patient consultations, interviews, and focus groups (FGs). The clinical audits included the number of women attending ANC visits in the Puskesmas; the number of women who received preeclampsia screenings using the checklist of clinical risk factors; the number of dipstick tests and amounts of antihypertensive medication prescribed; and the number of HDP women being referred to hospitals in a month. These data were extracted from the Puskesmas electronic information system at the end of the implementation period.

During the observation, the first author (observer) used the ‘observer as participants’ approach [25]. It is an approach that provides flexible opportunities for the observer to be involved in the participants' activities and have some interactions with them [25]. The observations were made after midwives and GPs in the Puskesmas notified the first author when they welcomed HDP patients or those with preeclampsia risk factors who consented to participate in the study. The participants were aware of the observation, and the observation video recordings were conducted with their permission. The observations were conducted twice, for an hour each, with 30 min of video recording (a total of 60 min recording) in each Puskesmas. Any significant but unrecorded observations were also noted in the first author’s fieldwork notes.

At the evaluation interviews/FGs, primary care provider participants were asked about their experience using the pathways, including implementation barriers and facilitators of the pathways in primary care. Obstetricians and local health officer participants were asked about their experience of receiving referrals for patients with HDP cases, including their views and suggestions for the future scale-up study. All FGs and interviews were conducted in Bahasa Indonesia by the first author to aid natural discussions with the participants and were conducted at the participating Puskesmas or by telephone, based on the participants’ preference. The core interview/FG questions used in this evaluation have previously been published in a study protocol paper [6] and the complete interview/FG questions in English have also been attached in Supplementary File 1.

Data analysis

Clinical audit data obtained in the study were analysed descriptively using Microsoft Excel software [26]. The numbers of women who visited for ANC in each Puskesmas, and who received any HDP screening, laboratory examinations and/or medications, were recorded and counted for their mean.

Qualitative data obtained from the observations, FGs, and interviews were analysed thematically. The thematic analysis process was performed as follows: (i) the FGs and interviews were transcribed and translated into English. (ii) Observation videos were described in English, viewed, and noted for any significant scenes; field notes taken during observations and the implementation were also translated into English. (iii) All transcripts, video descriptions and field notes were imported into Nvivo software [27] and were repeatedly read for data familiarisation. (iv) The data were then coded for any notable quotes, scenes, or notes and the codes were then grouped into overarching themes and subthemes according to PRISM domains [16] (deductive approach) as well as to elicit new themes (inductive approach) [15, 16]. The co-authors also validated the coding process and the results were discussed until coding consensus was agreed. Reporting of this study follows the Standards for Quality Improvement Reporting Excellence (SQUIRE) checklist [28] in Supplementary File 2.

Language validation

All PLSs, consent forms, implementation toolkits, and FG/interview questions were initially created in English, translated into Bahasa Indonesia, and then back-translated into English by the first author. An Indonesian native speaker then validated the translation of PLSs and consent forms to ensure language validation. All FG/interview transcripts in Bahasa Indonesia were also translated into English by the first author to aid discussion among the project investigators. A quarter of the transcripts were back-translated into Bahasa Indonesia by another native Indonesian speaker to ensure translation validation [29].

Results

Participants

Fifty primary care providers (16 GPs, 24 midwives, and ten nurses) from three participating Puskesmas, four obstetricians, one local health officer (a maternal health division officer), and 61 patients agreed to participate in this study (see Fig. 4). The majority of the clinicians were female (n = 46) and aged 20–40 years (n = 32), while the majority of patients were aged 20–30 years (n = 35), were housewives (n = 41), and had been registered in the Puskesmas for less than five years (n = 38). However, only 23 out of 61 patients provided their phone numbers for follow-up interview/FG arrangements. The participants’ recruitment flowchart and characteristics are presented in Fig. 4 and Table 1 and 2.

Fig. 4
figure4

Flowchart of participants recruitment to focus groups (FGs) and interviews

Table 1 Participants characteristic (health care providers)
Table 2 Participants characteristic (patients)

Results of the pathway implementation evaluation

Clinical audits

During the one-month intervention period, GPs, midwives, and nurses in three Puskesmas attempted to apply recommendations in the HDP pathways in various degrees (see Table 3). The most commonly applied recommendations were the preeclampsia risk factors screening (n = 141) and dipstick tests examination (n = 78). Some procedures of HDP management, such as the administration of aspirin (n = 24) and nifedipine prescriptions (n = 8), were also conducted by the Puskesmas. Puskesmas 1 had the highest percentage of preeclampsia risk factor screenings (82.14%), but Puskesmas 2 had the highest number of ANC visits and of low-dose aspirin prescriptions for preeclampsia prevention. Puskesmas 1 and 2 did not perform liver and kidney function tests due to limited clinical resources available in the clinics. However, all Puskesmas referred similar numbers of HDP patients to the hospital.

Table 3 Clinical audit data presenting number of women receive any examination or procedures according to the pathways

Observations

A total of six observations were conducted, and each Puskesmas had an hour of video-recording. Some notable observations were noted and are described below. It was challenging at the beginning of the implementation to engage Puskesmas staff because they had many patients and were busy with community outreach programs or Pos Pelayanan Terpadu (Posyandu) in the afternoon [30]. For this reason, a GP in Puskesmas 3 requested a risk-factor checklist to enable a more practical method of preeclampsia risk-factor screening in their patient encounters. Besides that, Puskesmas 2 already prescribed low-dose aspirin for women with a history of pregnancy hypertension, albeit before the study, it was prescribed only for a few days’ duration, and the patients were referred to the obstetricians. Meanwhile, the other two Puskesmas had only just initiated aspirin prophylaxis at the time of this study. Puskesmas 2 also had a visiting obstetrician who promoted aspirin prescription. All Puskesmas also provided home visits for pregnant women with HDP or preeclampsia risk factors, and these visits were embedded in their Posyandu schedules.

Focus groups (FGs) and interviews

A total of 43 clinicians and five patients participated in ten FGs and 13 interviews at the end of the implementation period. One FG and two interviews were conducted with primary care clinicians at Puskesmas 1; four FGs and one interview were conducted with clinicians at Puskesmas 2; and five FGs with clinicians at Puskesmas 3. Other interviews conducted consisted of four with obstetricians, one with the local health officer, and five with patients. All FGs consisted of two to six participants, and all participants only participated in one FG or interview each. The length of the FGs/interviews ranged from 15 to 60 min. All FGs/interviews were recorded and transcribed except for four interviews (three with obstetricians and one with a patient) due to the participants’ refusal for recording. Significant quotes during these four interviews were noted and presented afterward to the participants for content validation.

Themes arising from the analysis of observations, focus groups, and interview transcripts

Four themes were elicited from video-observation descriptions, and from FG and interview transcripts. The themes reflect successful impacts of the pathways, as well as notable barriers during the implementation of the pathways in primary care practice. Quotes supporting the themes are presented in Table 4.

Table 4 Quotes for each theme

Empowerment

This theme represents the successful impacts of the pathways, such as the providers’ positive experience and the sense of practice improvement by using the pathways in their practice. Almost all primary care provider participants in the FGs/interviews (n = 37, 92% of the interviewed primary care participants) expressed that content of the pathways was easy to follow and that it provided more comprehensive guidance on HDP management. The intervention toolkits such as posters, risk-factor checklists, and stickers were also able to remind the providers of important HDP recommendations. The providers also claimed that the current Indonesian ANC guidelines provided limited guidance on the follow-up procedures for women with preeclampsia risk factors, and that there had been no further firm guidance on HDP management in the Puskesmas or from the local health office before the study.

Many primary care provider participants (n = 37, 92% of the interviewed primary care participants) also felt that the pathways enabled them to improve their HDP management, via means such as calcium supplementation and low-dose aspirin prescriptions. The providers were now also able to request appropriate blood examinations for preeclampsia monitoring, whereas previously, they only could monitor the women’s condition mainly with blood pressure measurement and dipstick proteinuria tests. Some participants (n = 17) then went further, saying that the pathways helped them to practice optimally under the JKN insurance regulations, which required them to manage patients appropriately in primary care.

Some notes from the observations also support this theme. One woman presented to Puskesmas 3 in her 35th week of pregnancy and had impending preeclampsia symptoms of edema in both legs, tremors, and ‘pins and needles’ sensations in her fingers. There was considerable confusion amongst the GPs and midwives about whether to refer the patient immediately or ask her to consult a specialist at her next hospital appointment. The GPs then decided to follow instructions in the pathway and requested kidney and liver function tests, which showed abnormal creatinine results. The patient was then immediately transferred to a hospital and safely gave birth two days after the admission.

Hierarchy

Hierarchical interprofessional relationships between the providers were a prominent challenge of the pathway implementation that was mentioned in almost all interviews and FGs with clinician participants. Firstly, there were implicit professional boundaries that existed in the Puskesmas. The ANC visits in Puskesmas were conducted mainly by midwives. Women were only occasionally referred to GPs, and rarely saw nurses during their routine visits. They would only see GPs at their first ANC visit, or if they had morbidities, as only GPs could prescribe medications for pregnancy or refer the women to hospitals.

Secondly, there was a sense of imbalanced hierarchical positions between GPs and patients in the Puskesmas during the pathway implementation. At the interviews, many providers mentioned that patients were very compliant with their advice, including undergoing laboratory examinations and taking medicine prescriptions. However, some patients expressed concerns to the midwives on receiving the medications but avoided discussing them with their GPs. A woman in Puskesmas 2 was anxious about her prescription, as she thought she was asymptomatic of pregnancy hypertension. Another woman, in Puskesmas 3, was initially crying after being told that she had to be referred to a hospital immediately. She thought she was still far from her delivery, and reported that the obstetricians and GPs did not explain her preeclampsia conditions. These two women were silent during the consultation; however, they expressed their concerns outside the GP room. They finally obeyed the GPs’ advice after being further approached and calmed by midwives. Later, the woman in Puskesmas 2 agreed with the medication and the woman in Puskesmas 3 agreed to have emergency delivery at the hospital.

Thirdly, a hierarchical imbalance also existed between GPs and specialists, which affected prescriptions of HDP medications. Several GPs (n = 6) argued that they were inexperienced and were afraid of encroaching upon specialists’ authority in obstetrics cases. However, they also voiced their concerns that JKN did not permit referrals of patients if they were asymptomatic or ineligible for HDP diagnosis. The GPs then further mentioned their frequent dilemma as the obstetricians’ discharge notes were unclear, but the patients had returned to primary care for further monitoring. Concerning this situation, some obstetricians (n = 3) supported the GPs by encouraging them to perform more HDP management; but still, they stressed the importance of obstetrician consultations, suggesting that GPs should always refer their HDP patients to hospitals (Table 4).

Fourthly, hierarchical barriers were observed between clinicians and the local health office. Most of the Puskesmas staff were public employees and the local health office coordinated their employability. Some GPs expressed their hesitance to manage HDP and thus contradict the local health policy, which ordered them to refer women with any pregnancy complications to hospitals.

Clinical resources

Clinical resources appeared to be another barrier for the pathway implementation, even though they did not impede implementation to the degree of the interprofessional hierarchy above. It was observed that Puskesmas had adequate supplies of aspirin and resources for electronic laboratory examinations for recommendations in the pathways. However, some GPs (n = 4) mentioned that the availability of testing reagents might deplete if many women had to undertake weekly preeclampsia blood tests. They also thought that the Puskesmas might have to demand more aspirin from the health office if it were to be given to eligible women up to the 37th week of pregnancy or until delivery.

Direction

All participants expressed positive views regarding the possibility of the scale-up study of the pathways, as it would enhance the pathways’ value and practice uniformity in the region. Before the scale-up study, some obstetricians (n = 3) suggested revising terminologies used in the pathways in order that they be congruent with the existing Indonesian diagnostic standards. It was due to this disparity in terminology that some HDP diagnoses, such as eliminating transient hypertension or masked hypertension, were not found in the Indonesian e-medical records. Some GPs and midwives further suggested advocacy for supporting policies with local health officers and involving champion obstetricians to endorse the pathways’ uptake in primary care. More educational activities and toolkits, such as teaching, training, posters, and booklets, were also suggested to increase midwives and nurses’ skills and enhance patient awareness in HDP management.

Discussion

This study has reported an implementation process to determine the acceptability and feasibility of HDP management pathways in Indonesian primary care. The pathways are acceptable, feasible, and have empowered the providers’ practice in HDP management, despite some practical challenges of clinical resources and professional hierarchies. There are also opportunities and suggestions for the scale-up study of the pathways by involving champion obstetricians, developing supporting policies, and providing more patients educational tools.

The underpinning theoretical frameworks of MRC and PRISM [15, 16] have helped the understanding of the pathways’ implementation process. As the primary intervention, the developed HDP pathways are able to complement current Indonesian ANC standards and improve the providers’ ability in HDP management. Knowledge transfer and dissemination process of the pathways have also been facilitated by the multifaceted intervention toolkits provided in the study, including training modules, posters, and the use of a preeclampsia risk factor checklist. The JKN policy has also facilitated the pathway implementation, through its requirement that the providers should manage patients appropriately in primary care practice.

Some intrinsic characteristics of the primary care provider participants have also supported the pathway implementation. The providers were open to expanding and were willing to elevate their practice by performing more HDP management, including HDP screenings and prescribing aspirin for preeclampsia prophylaxis. They felt empowered to challenge the status quo of HDP management in primary care, which is often hampered by professional hierarchies, rigid regulations, and limited clinical resources.

Nonetheless, there are also barriers of prominent professional boundaries and hierarchy that challenge the pathway implementation in primary care; and these barriers are not uncommon for any intervention implementation in health care settings [31]. However, the hierarchical barrier is very prominent in the Indonesian context, in which the study took place [32, 33], outweighing other classical barriers of implementation in LMICs, such as limited clinical resources and facilities [34, 35]. Nurses and midwives in Indonesia are usually positioned at a lower hierarchical level than GPs, and GPs often feel inferior to and less qualified than specialists [36]. The GPs’ confidence to apply recommendations in the pathways can easily crumble after receiving unsupportive policies from or having demotivating experiences with obstetricians, who are perceived as the ultimate experts in maternal health [37].

The power imbalance between clinicians described above may have resulted from the disparities in clinicians’ respective levels of training. Practicing nurses or midwives are usually diploma graduates in nursing or midwifery [38], and Indonesian GPs are medical doctor (MD) graduates without any further postgraduate training. However, to practice as specialists, the MD graduates have to undertake a further three to four years of specialty training in hospitals [38, 39]. Therefore, many GPs, nurses, and midwives often feel less capable, less respected and/or less trusted than specialists, and often receive less acknowledgement from specialists or patients [40, 41].

In addition, some of our findings also indicate a sense of resignation of primary care situations that represents a system issue in Indonesian health care. Some participants expressed their clinical inertia by referring to limited clinical resources available in primary care, even though some medicines and reagents were affordable and available in Puskesmas. Therefore, if the Indonesian government desperately wants to accelerate maternal mortality reduction, the health policies must consider the long-term benefits of HDP management in primary care by reinforcing policies to support primary care practice [42].

Strengths and limitations

Key strengths of the study are that it has a rigorous study design, and that it applied multifaceted intervention toolkits to optimise the participants’ exposure to the pathways [43,44,45]. The evaluation of the pathway implementation also involved triangulation of clinical audits, observations, and FGs/interviews to allow in-depth analysis and to complement findings from each evaluation method [46]. The number of participants in the study was considerable and provided similar implementation evaluations, which optimises our confidence in the data saturation. The FGs were also conducted with participants in the same professional group to minimise biases and power imbalance of dominant participants [47]. The first author, who is an Indonesian GP researcher, conducted the dissemination seminars and all FGs/interviews. Her experience of working with and interviewing primary care providers has also enabled candid responses from the participants during the FGs/interviews.

However, due to the short implementation period, not many patient participants provided their contact for interview arrangements, which limited the opportunities to listen to their evaluation for the pathways [12]. Lastly, the pathways were only implemented in three Puskesmas in Yogyakarta province, which may not represent situations in private practices or other Indonesian provinces.

Implications for practice

This study has shown that the developed HDP management pathways are feasible and acceptable for their implementation in Indonesian primary care. The pathways can be used to inform policy or to guide local health offices to improve HDP management in primary care. Results of pathway implementation in this study can also be used as to inform strategy to reduce maternal mortality in Indonesia or other LMICs with similar contexts [48, 49].

Implications for future research

Our study has identified key barriers to the pathways’ implementation feasibility in primary care. According to the MRC guidelines [15], future research should examine strategies to minimise these barriers before conducting further study into pathways efficacy or more extensive implementation studies to enhance the pathways’ values in primary care practice. Professional boundaries and hierarchical barriers as the prominent challenge of pathway implementation could potentially be minimised by providing interprofessional training that enables knowledge sharing between the providers [50]; or, as mentioned by the participants in this study, by involving champion obstetricians and advocating supporting policies to endorse the pathway uptakes in primary care [15, 51].

Conclusion

This study has determined the acceptability and feasibility of the developed HDP management pathways in Indonesian practice, and has provided foundations for further research in primary care. Notable challenges of the pathway implementation have also been identified, such as professional boundaries and hierarchy among the providers. Further investigations to minimise the implementation barriers are desired before conducting scale-up implementation of the pathway in primary care.

Availability of data and materials

Raw materials in this study contain confidential and private information. They are not suitable to share beyond the research team.

Abbreviations

ANC:

Antenatal care

GPs:

General practitioners

HDP:

Hypertensive disorders of pregnancy

LMICs:

Low-and middle-income Countries

JKN:

Jaminan Kesehatan Nasional (Indonesian national public insurance)

PLS:

Plain Language Statement

Posyandu:

Pos Pelayanan Terpadu (Community outreach program)

Puskesmas:

Pusat Kesehatan Masyarakat (Indonesian public primary care clinic)

SOP:

Standard Operating Procedures

References

  1. 1.

    Say L, Chou D, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health. 2014;2(6):e323–33. https://doi.org/10.1016/S2214-109X(14)70227-X.

    Article  Google Scholar 

  2. 2.

    Brown MA, Magee LA, et al. The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice. Pregnancy Hypertens. 2018;13:291–310. https://doi.org/10.1016/j.preghy.2018.05.004.

    CAS  Article  PubMed  Google Scholar 

  3. 3.

    World Health Organization (WHO). Maternal Mortality Key Facts: WHO; 2018 [updated; cited 2018. Available from: http://www.who.int/news-room/fact-sheets/detail/maternal-mortality. 7 June 2018

  4. 4.

    Ministry of Health Republic Indonesia. Indonesian Health Profiles: Data and Information (Data dan Informasi tahun 2015 Profil Kesehatan Indonesia). Jakarta: Indonesian Ministry of Health Health Do; 2016. http://www.depkes.go.id/resources/download/pusdatin/lain-lain/Data%20dan%20Informasi%20Kesehatan%20Profil%20Kesehatan%20Indonesia%202016%20-%20%20smaller%20size%20-%20web.pdf.

    Google Scholar 

  5. 5.

    Firoz T, Harshad S, et al. Pre-eclampsia in low and middle income countries. Best Pract Res Clin Obstetr Gynaecol. 2011;25(4):537–48. https://doi.org/10.1016/j.bpobgyn.2011.04.002.

    Article  Google Scholar 

  6. 6.

    Ekawati FM, Licqurish S, et al. Developing management pathways for hypertensive disorders of pregnancy (HDP) in Indonesian primary care: a study protocol. Reprod Health. 2019;16(1):12. https://doi.org/10.1186/s12978-019-0674-0.

    Article  PubMed  PubMed Central  Google Scholar 

  7. 7.

    Kulonprogo Local Health Office. Referral Manual for Pregnancy, Labor, Delivery and Newborn Care, according to the Technical Procedure of Jampersal and Situation at Kulonprogo District Kulon Progo Yogyakarta. 2012. http://kebijakankesehatanindonesia.net/v13/images/manualrujuk/MANUAL%20RUJUKAN%20KEHAMILAN%20KULON%20RPOGO%20FINAL.pdf. 19 September 2019.

  8. 8.

    World Health Organization-South-East Asia Regional Office (WHO-SEARO), Kementerian Kesehatan Republik Indonesia, et al.2013. Buku Saku Pelayanan Kesehatan Ibu di Fasilitas Kesehatan Dasar dan Rujukan. http://www.searo.who.int/indonesia/documents/976-602-235-265-5-buku-saku-pelayanan-kesehatan-ibu.pdf?ua=1. 18 August 2017

  9. 9.

    Yuli M, Utarini A, et al. Maternal care quality in near miss and maternal mortality in an academic public tertiary hospital in Yogyakarta, Indonesia: a retrospective cohort study. BMC Pregnancy Childbirth. 2017;17:149. https://doi.org/10.1186/s12884-017-1326-4.

    Article  Google Scholar 

  10. 10.

    Baharuddin M, Amelia D, et al. Maternal death reviews: A retrospective case series of 90 hospital-based maternal deaths in 11 hospitals in Indonesia. Int J Gynecol Obstetr. 2019;144(S1):59–64. https://doi.org/10.1002/ijgo.12736.

    Article  Google Scholar 

  11. 11.

    Ekawati FM, Emilia O, et al. Opportunities for improving hypertensive disorders of pregnancy (HDP) management in primary care settings: A review of international published guidelines in the context of pregnancy care in Indonesia. Pregnancy Hypertension. 2020;19:195–204. https://doi.org/10.1016/j.preghy.2020.01.012.

    Article  PubMed  Google Scholar 

  12. 12.

    Ekawati FM, Licqurish S, et al. Management of hypertensive disorders of pregnancy (HDP) in Indonesian primary care settings: the views of stakeholders. Austr J Prim Health. 2019;25(3):XIV Abstracts of the AAAPC Annual Research Conference, Adelaide 2019.

    Google Scholar 

  13. 13.

    Widyaningsih V, Khotijah, et al. Expanding the scope beyond mortality: burden and missed opportunities in maternal morbidity in Indonesia. Glob Health Action. 2017;10(1):1339534. https://doi.org/10.1080/16549716.2017.1339534.

    Article  PubMed  PubMed Central  Google Scholar 

  14. 14.

    Ministry of Health Republic Indonesia. Peraturan Menteri Kesehatan Republik Indonesia Nomor 28 Tahun 2017 tentang izin dan penyelenggaraan praktik bidan (Regulation of the Minister of Health of the Republic of Indonesia Number 28 of 2017 concerning licensing and implementation of midwifery practices). Jakarta. 2017. http://www.ibi.or.id/media/PMK%20No.%2028%20ttg%20Izin%20dan%20Penyelenggaraan%20Praktik%20Bidan.pdf. 4 September 2019.

  15. 15.

    Craig P, Dieppe P, et al. Developing and evaluating complex interventions: the new Medical Research Council guidance. Int J Nurs Stud. 2013;50(5):587–92.

    Article  Google Scholar 

  16. 16.

    Feldstein AC, Glasgow RE. A practical, robust implementation and sustainability model (PRISM) for integrating research findings into practice. Joint Commission J Qual Patient Safety. 2008;34(4):228–43.

    Article  Google Scholar 

  17. 17.

    Ministry of Health Republic Indonesia. Maternal death surveillance guideline (Pedoman surveilans kematian ibu). Jakarta. 2016. https://indonesia.unfpa.org/sites/default/files/pub-pdf/MHH_MDSR_NationalGuidelines_20161222_final.pdf. 12 February 2019.

  18. 18.

    Dinas Kesehatan Propinsi Yogyakarta (Yogyakarta Local Health Office). Profil Kesehatan Provinsi di Yogyakarta Tahun 2017. 2017. https://www.kemkes.go.id/resources/download/profil/PROFIL_KES_PROVINSI_2017/14_DIY_2017.pdf. 25 February 2019.

  19. 19.

    Direktorat Kesehatan Ibu Kementerian Kesehatan Republik Indonesia. Tren data kematian dan penyebab kematian ibu 2016–2019. Jakarta. 2020.

  20. 20.

    Ministry of Health Republic Indonesia. The Ministry of Health Regulation number 28 year 2014 about the implementation guideline of Indonesian universal health coverage. Jakarta. 2014. http://dinkes.mataramkota.go.id/wp-content/uploads/2016/05/PMK-No.-28-Th-2014-ttg-Pedoman-Pelaksanaan-Program-JKN.pdf.

  21. 21.

    Agustina R, Teguh D, et al. Universal health coverage in Indonesia: concept, progress, and challenges. Lancet. 2018. https://doi.org/10.1016/S0140-6736(18)31647-7

  22. 22.

    Ekawati FM, Licqurish S, et al. Hypertensive disorders of pregnancy (HDP) management pathways: results of a Delphi survey to contextualise international recommendations for Indonesian primary care settings. BMC Pregnancy Childbirth. 2021;21(1):269. https://doi.org/10.1186/s12884-021-03735-3.

    Article  PubMed  PubMed Central  Google Scholar 

  23. 23.

    Houman Pournasseh, Murphy, Brian, et al. Short message system for mobile devices. Google Patents; 2010.

  24. 24.

    Jan Koum, Acton, Brian WhatsApp [Available from: https://www.whatsapp.com/about/. 5 June 2020

  25. 25.

    Barbara B. Kawulich. Participant observation as a data collection method. 2005;6(2). https://doi.org/10.17169/fqs-6.2.466

  26. 26.

    Microsoft.Microsoft Excel 365 (Software). https://www.microsoft.com/en-au/microsoft-365/excel.

  27. 27.

    QSR International. 2019. Nvivo (Software) version 12.2.0 (3262). https://www.qsrinternational.com/nvivo-qualitative-data-analysis-software/support-services/nvivo-downloads.

  28. 28.

    Ogrinc G, Mooney SE, et al. The SQUIRE (Standards for QUality Improvement Reporting Excellence) guidelines for quality improvement reporting: explanation and elaboration. Qual Safety Health Care. 2008;17(Suppl 1):i13. https://doi.org/10.1136/qshc.2008.029058.

    Article  Google Scholar 

  29. 29.

    Douglas SP, Samuel CC. Collaborative and iterative translation: An alternative approach to back translation. J Int Market. 2007;15(1):30–43.

    Article  Google Scholar 

  30. 30.

    Leimena SL. Posyandu: a community based vehicle to improve child survival and development. Asia-Pacific J Publ Health. 1989;3(4):264–7. https://doi.org/10.1177/101053958900300402.

    CAS  Article  Google Scholar 

  31. 31.

    Lau R, Stevenson F, et al. Achieving change in primary care—causes of the evidence to practice gap: systematic reviews of reviews. Implement Sci. 2016;11(1):40. https://doi.org/10.1186/s13012-016-0396-4.

    Article  PubMed  PubMed Central  Google Scholar 

  32. 32.

    Claramita M, Riskiyana R, et al. Interprofessional communication in a socio-hierarchical culture: development of the TRI-O guide. J Multidiscip Healthc. 2019;12:191–204. https://doi.org/10.2147/JMDH.S196873.

    Article  PubMed  PubMed Central  Google Scholar 

  33. 33.

    Claramita M, Susilo AP. Improving communication skills in the Southeast Asian health care context. Perspect Med Educ. 2014;3(6):474–9. https://doi.org/10.1007/s40037-014-0121-4.

    Article  PubMed  PubMed Central  Google Scholar 

  34. 34.

    Santesso N, Tugwell P. Knowledge translation in developing countries. J Continuing Educ Health Prof. 2006;26(1):87–96.

    Article  Google Scholar 

  35. 35.

    Baradaran-Seyed Z, Nedjat S, et al. Barriers of clinical practice guidelines development and implementation in developing countries: a case study in Iran. Int J Prev Med. 2013;4(3):340.

    PubMed  PubMed Central  Google Scholar 

  36. 36.

    Dewi WN, Evans D, et al. Person-centred care in the I ndonesian health-care system. Int J Nurs Pract. 2014;20(6):616–22.

    Article  Google Scholar 

  37. 37.

    Stokes T, Shaw EJ, et al. Barriers and enablers to guideline implementation strategies to improve obstetric care practice in low- and middle-income countries: a systematic review of qualitative evidence. Implement Sci. 2016;11(1):144. https://doi.org/10.1186/s13012-016-0508-1.

    Article  PubMed  PubMed Central  Google Scholar 

  38. 38.

    Ekawati FM. Patients' experience of using primary care in the context of Indonesian universal health coverage implementation: an interpretative phenomenological analysis. 2015.

  39. 39.

    Ekawati FM, Claramita M, et al. The Indonesian general practitioners’ perspectives on formal postgraduate training in primary care. Asia Pacific Fam Med. 2018;17(1):10.

    Article  Google Scholar 

  40. 40.

    Istiono W, Claramita M, et al. Physician's self-perceived abilities at primary care settings in Indonesia. J Fam Med Prim Care. 2015;4(4):551–8.

  41. 41.

    Ekawati FM, Claramita M, et al. Patients’ experience of using primary care services in the context of Indonesian universal health coverage reforms. Asia Pacific Fam Med. 2017;16:4. https://doi.org/10.1186/s12930-017-0034-6.

    Article  Google Scholar 

  42. 42.

    Ekawati FM, Lau P. Short communication: What if there is no reliable and appropriate medication for pregnancy hypertension available in Indonesian primary care? Pregnancy Hypertens. 2020;21:68–9. https://doi.org/10.1016/j.preghy.2020.04.017.

    Article  PubMed  Google Scholar 

  43. 43.

    Squires JE, Sullivan K, et al. Are multifaceted interventions more effective than single-component interventions in changing health-care professionals' behaviours? An overview of systematic reviews. Implement Sci. 2014;9(1):152. https://doi.org/10.1186/s13012-014-0152-6.

  44. 44.

    Wensing M, Glidewell L, et al. Effectiveness and efficiency of guideline dissemination and implementation strategies. 2004.

    Google Scholar 

  45. 45.

    Grol R, Grimshaw J. From best evidence to best practice: effective implementation of change in patients' care. Lancet. 2003;362(9391):1225–30. https://doi.org/10.1016/S0140-6736(03)14546-1.

  46. 46.

    Hamilton AB, Finley EP. Qualitative methods in implementation research: An introduction. Psych Res. 2019;112516:463.

    Google Scholar 

  47. 47.

    Breen RL. A practical guide to focus-group research. J Geography Higher Educ. 2006;30(3):463–75.

    Article  Google Scholar 

  48. 48.

    Willcox ML, Price J, Scott S, et al. Death audits and reviews for reducing maternal, perinatal and child mortality. Cochrane Database Syst Rev. 2020;3(3):CD012982. https://doi.org/10.1002/14651858.CD012982.pub2.

  49. 49.

    World Health Organization. Maternal death surveillance and response: technical guidance information for action to prevent maternal death. 2013.

    Google Scholar 

  50. 50.

    Kislov R, Walshe K, et al. Managing boundaries in primary care service improvement: a developmental approach to communities of practice. Implement Sci. 2012;7(1):97.

    Article  Google Scholar 

  51. 51.

    Bate P. Chapter 13 - Designing an effective approach to cultural change. In: Bate P, editor. Strategies for Cultural Change. Oxford: Butterworth-Heinemann; 1996. p. 212–234.

Download references

Acknowledgements

The authors thank all participants in this study for their participation and acknowledge the additional advice provided by Dr Rukmono Siswishanto from Sardjito Tertiary Hospital, Yogyakarta regarding interprofessional relationships among health care workers in Indonesia.

Funding

The first author received Lembaga Pengelola Dana Pendidikan (LPDP) postgraduate scholarship from the Indonesian Ministry of Finance. The research expenditure was also partly supported by the Peter McPhee Student Award from The University of Melbourne.

Author information

Affiliations

Authors

Contributions

All authors were involved in the study design and analysis. FE did the data collection, OE provided essential feedback during the data collection process. FE drafted the initial manuscript, and SL, JG, and PL provided significant feedback during the manuscript development. All authors in this study have read the final manuscript and agreed to its submission for publication.

Corresponding author

Correspondence to Fitriana Murriya Ekawati.

Ethics declarations

Ethics approval and consent to participate

Ethics approvals for this study were obtained from Medicine and Dentistry Human Ethics Sub-Committee, The University of Melbourne, Melbourne, Australia (ID: 1954401.1) and Ethics Commission, Faculty of Medicine, Public Health and Nursing at Universitas Gadjah Mada, Sleman, Yogyakarta, Indonesia (ID. KE/FK/0881/EC/2019). A permit to research in the three Puskesmas has been obtained from Bappeda Office in Bantul, Yogyakarta, Indonesia, number 070/ Reg/ 1801/ DSN/ 2019. The head of each Puskesmas has provided their written consent to represent the Puskesmas agreement to participate in the study and their medical records to be reviewed. All participants have provided written consent to participate in the study.

Consent for publication

All participants have provided consent for their de-identified responses to be published in academic journals or conferences.

Competing interests

The authors declare no competing interest in this study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Additional file 1: Supplementary Table 1

. Guiding questions used in the evaluation interviews/focus groups.

Additional file 2.

Reporting checklist for quality improvement study.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Ekawati, F.M., Emilia, O., Gunn, J. et al. Challenging the status quo: results of an acceptability and feasibility study of hypertensive disorders of pregnancy (HDP) management pathways in Indonesian primary care. BMC Pregnancy Childbirth 21, 507 (2021). https://doi.org/10.1186/s12884-021-03970-8

Download citation

Keywords

  • Hypertensive disorders of pregnancy
  • Preeclampsia
  • Indonesia
  • Management
  • Implementation
  • Barriers
  • Acceptability
  • Feasibility
  • LMICs
  • Primary care