The effect of an elective cesarean section on maternal request on peripartum anxiety and depression in women with childbirth fear: a systematic review

In the past few decades, cesarean section rates have steadily increased worldwide, and in many places they exceed 20% of all deliveries [1–10]. Although cesarean sections can prevent maternal and perinatal mortality and morbidity, they are also associated with short-term and long-term risks which can extend many years beyond the current delivery and affect the health of the woman and her child as well as future pregnancies [11–17]. Besides health risks, a cesarean birth is also associated with higher costs [3, 11].

The rising numbers are partly due to the rising number of women requesting an elective cesarean section (ECS) [12, 18–20]. ECS on maternal request only are internationally estimated at 1 to 9% of all cesarean deliveries [17, 18, 21–23]. Often this request is due to psychosocial reasons [12, 18–20] and more specifically to fear of childbirth, which is experienced by approximately 20% of all pregnant women, with 6% to 10% experiencing severe childbirth fear [12, 18, 24]. These women are not only more likely to request a cesarean section [25–27] but are also more likely to receive an ECS [21, 28, 29]. Often, they are known with a psychiatric disorder and/or symptomatology [18, 30].

Because of the increased obstetric risks associated with cesarean sections, obstetricians are often reluctant to grant the wish for an ECS. On the other hand, obstetricians’ insistence on a vaginal delivery could induce additional stress and possibly increase the risk for peripartum anxiety and depression. To date, it is unknown if the prospect of an ECS on request improves mental well-being in the mother in the peripartum period and if possible beneficial effects on anxiety and depression could outweigh the increased risk of complications associated with a surgical delivery [16].

While other articles and systematic reviews concentrated mostly on the exploration of the effect of psychological or supportive interventions during pregnancy in women with childbirth fear [31–33], this systematic review was conducted to explore the impact of the prospect of an ECS itself as a possible intervention in the treatment of anxiety and depressive disorders during pregnancy. The control group consisted of women without a wish for ECS with a normal vaginal delivery.

We formulated the following research questions:

1. What is the effect of an ECS on maternal request on postpartum anxiety and depression levels in women with childbirth fear?

2. How do depression and anxiety levels develop peripartum in women with childbirth fear with an ECS on maternal request?

PRISMA-guidelines [34] were followed. The research protocol was registered at PROSPERO (registration number: CRD42016041342).

Study selection

Two reviewers independently assessed inclusion eligibility. Initial selection for inclusion was based on screening of titles. Thereafter, included titles were screened on abstract. Abstracts were included if they mentioned depression and/or anxiety AND ECS/cesarean section on request. Following this, full-text versions of the selected studies were assessed for eligibility. Disagreement about inclusion was solved through discussion. Exclusion criteria are shown in Fig. 1. Studies were only included if they used validated screening tools, and studies would be compared by differences in mean scores. We tried to contact the first author if part of the needed data was missing.

The focus of this review was the effect of an ECS on maternal request on the mother’s peripartum anxiety and depression levels in women with childbirth fear. Antepartum depression and anxiety scores remained high in women requesting and receiving an ECS, but postpartum depression scores were the same as in women without a wish for ECS who delivered vaginally. These findings are supported by eight studies [9, 12, 43, 44, 51–54] of adequate quality that combined data of ECS on medical indication and on maternal request (data and quality assessment not shown). One study of 112 women with a wish for ECS but who delivered vaginally, reported higher scores for depression and PTSD after childbirth [36].

The fact that antepartum scores of anxiety or depression remain high in women with childbirth fear despite the prospect of an ECS are in line with other studies measuring antepartum anxiety levels in women undergoing an ECS [18, 19, 55, 56].

Because none of the studies had data prior to conception, we cannot conclude whether depressive women more often request an ECS or if childbirth fear itself leads to depressive symptoms. The study of Størksen et al. [18] concluded that women who requested an ECS had several vulnerability characteristics, such as poor mental health, previous negative overall birth experiences and poor social support. A mismatch in wish and actual delivery mode seems to be an extra stressor for these vulnerable women. The only included study that explicitly focused on ‘mismatches’ is the study of Garthus-Niegel et al. [36]. Their results show that granting the maternal request for an ECS may lower the risk of developing PTSD and postpartum depression in these women. Comparison of the ECS match group (wish for ECS granted) and the mismatch group (preference for ECS, but not performed) showed a trend of higher PTSD symptoms postpartum in the mismatch group (IES is 7.7 in match group versus 10.83 in mismatch group (p = 0.018 and 0.11 after post hoc Bonferroni tests)). There also was a trend towards higher postpartum depression levels in the mismatch group (EPDS is 4.58 in the match group versus 5.87 in the mismatch group), but these differences were not statistically significant (p = 0.066, no post hoc tests were applied)). This may have been due to a lack of power, as the match group consisted of only 53 women and the mismatch group consisted of 112 women (versus 1493 women in the group of normal vaginal delivery, whose PTSD and depression levels were significantly lower than those of the mismatch group but similar to those of the match group). Also, post hoc Bonferroni tests were used.

Another mismatch that could be evaluated are women who prefer a vaginal delivery but deliver through cesarean section. The study of Houston et al. [57] showed that a stronger preference for vaginal delivery was associated with higher depression scores postpartum among women who underwent cesarean section, indicating that it may not be the delivery method itself that induces stress, but the mismatch in expectations.

The question that remains is the meaning of these findings for clinical practice, given the present limited data. Emphasizing the risk of a cesarean section does not seem to be sufficient to persuade all women to deliver vaginally if this is medically viable. Rather, fear of childbirth and a maternal request for ECS should be taken seriously and should be further explored. In daily practice, routine screening of women who request an ECS should be considered, for example with a questionnaire like the SCL-8 [46]. If a woman scores above cut-off, further evaluation by a psychiatrist or psychologist is needed, as research has shown that self-reported screening tools for perinatal depression yield a higher rate of positive cases than clinical interview methods [41]. However, if a woman resolutely persists in her wish for ECS despite counselling and/or psychiatric treatment, the risk of developing depressive and PTSD symptoms should be taken into account, and consequently an ECS may be considered as a valid option.

The best psychiatric treatment of childbirth fear is still under debate. Several options have been described, and some studies have shown that at least half of the women can prepare for a normal vaginal delivery and that the rate of vaginal deliveries increased after treatment by group psychoeducation combined with relaxation exercises [31, 32]. Other studies that evaluated treatment of childbirth fear by supportive, psychotherapeutic or cognitive treatment did not show a decrease in ECS rates [24, 58] nor a more positive experience of delivery [33]. A comprehensive systematic review of Weaver et al. [59] on the impact of planned interventions offered to women requesting an ECS concluded that more research is needed to identify how tokophobic women might best be helped.

There are several strengths and limitations to this review. To the best of our knowledge, this is the first systematic review on the effect of an ECS on maternal request on peripartum anxiety and depression. A qualitative appraisal of the studies made it possible to highlight the studies with the best quality. We did not include the studies that combined data of ECS on medical indication and on maternal request. More research is needed specifically concerning ECS on maternal request, including the focus on mismatches between the maternal wish and actual mode of delivery. It is important that these studies contain information on the mental health of pregnant women prior to delivery, to assure that possible differences in mental health postpartum may not just reflect pre-existing differences between the groups. Data about the motivation for requesting an ECS should be included, as should data about adequate counselling about the risks of surgical delivery. Clarification of obstetric factors would further strengthen such research.

Women who requested an ECS had higher antepartum depression and anxiety levels than women who had planned to deliver vaginally. If the request for ECS was granted, their antepartum depression and anxiety levels did not decline, but postpartum depression levels reverted to normal. One study of good quality reported that, if ECS was not granted, women who persisted in preferring ECS had significantly higher symptom levels of post-traumatic stress disorder (PTSD) and depression after vaginal delivery than women who had planned on vaginal delivery. For clinical practice, given these limited data, this means that this vulnerable group of women need adequate counselling and psychiatric treatment for possible anxiety and/or depressive disorder. However, if women resolutely persist in their wish for a cesarean section, an ECS may be considered as a valid alternative.