Table 3 Median hormone concentrations (10–90th percentiles) overall and by parity ^a

 1st trimester

2.18 (1.16–3.59)

2.11 (1.19–4.00)

2.42 (1.12–3.12)

0.92

 2nd trimester

9.71 (5.33–15.1)

10.3 (5.20–14.8)

9.45 (5.46–15.3)

0.64

 3rd trimester

20.4 (12.8–32.9)

22.3 (13.6–35.6)

19.5 (12.8–31.5)

0.71

Median %-change ^b

876 %

858 %

889 %

 1st trimester

0.93 (0.41–1.72)

0.71 (0.35–2.07)

1.11 (0.48–1.60)

0.14

 2nd trimester

4.28 (1.99–8.54)

3.96 (1.64–8.84)

4.56 (2.77–6.88)

0.85

 3rd trimester

11.5 (3.70–18.9)

10.4 (3.65–21.3)

11.7 (3.77–17.8)

0.92

Median %-change ^b

976 %

919 %

1053 %

 1st trimester

25.6 (16.6–40.7)

27.3 (20.0–42.2)

23.0 (13.5–37.8)

0.03

 2nd trimester

48.1 (31.6–78.5)

53.8 (37.8–85.2)

42.1 (28.7–71.3)

0.03

 3rd trimester

130 (72.6–200)

138 (105–215)

107 (60.2–163)

0.007

Median %-change ^b

411 %

422 %

396 %

 1st trimester

0.96 (0.42–1.98)

1.34 (0.78–2.15)

0.66 (0.36–1.11)

<0.0001

 2nd trimester

1.19 (0.55–3.35)

1.98 (1.05–3.96)

0.73 (0.44–1.43)

<0.0001

 3rd trimester

1.32 (0.50–4.07)

2.56 (0.54–6.06)

0.71 (0.50–2.41)

0.0008

Median %-change ^b

61 %

74 %

38 %

 1st trimester

28.8 (16.3–57.6)

32.6 (19.8–63.3)

27.6 (10.6–47.0)

0.10

 2nd trimester

126 (54.9–206)

105 (49.0–181)

139 (72–206)

0.32

 3rd trimester

216 (124–318)

177 (115–258)

225 (133–320)

0.12

Median %-change ^b

570 %

449 %

795 %

 1st trimester

3.79 (2.63–5.90)

3.45 (2.71–5.61)

3.93 (2.37–5.99)

0.21

 2nd trimester

5.26 (3.10–7.91)

4.96 (3.28–7.15)

6.01 (3.10–9.01)

0.17

3rd trimester

9.74 (4.44–17.5)

8.18 (4.09–20.3)

10.5 (5.59–16.4)

0.12

Median %-change ^b

143 %

112 %

162 %

 1st trimester

0.43 (0.10–0.81)

0.32 (0.06–0.92)

0.56 (0.31–0.74)

0.04

 2nd trimester

0.43 (0.10–0.91)

0.31 (0.06–1.05)

0.51 (0.27–0.81)

0.26

 3rd trimester

0.43 (0.20–0.82)

0.41 (0.14–0.95)

0.43 (0.30–0.72)

0.35

Median %-change ^b

8 %

30 %

−14 %