Table 4 KEGG pathway analysis of cord blood metabolites associated with the excessive GWG group versus the control group
KEGG Pathway | Screened Metabolites | P value | Trend | Mode |
|---|---|---|---|---|
Biosynthesis of unsaturated fatty acids | Stearic acid; Erucic acid; Palmitic acid; Lignoceric Acid; Docosanoic Acid; Docosahexaenoic acid; Arachidonic acid; Adrenic acid; Docosapentaenoic acid | 0.00 | Up | Negative |
Ferroptosis | Arachidonic acid; Adrenic acid | 0.06 | Up | Negative |
Ovarian steroidogenesis | 17α-Hydroxypregnenolone; Arachidonic acid | 0.06 | Up | Negative |
Cortisol synthesis and secretion | 17α-Hydroxypregnenolone; Hydrocortisone | 0.06 | Up | Negative |
Cushing’s syndrome | 17α-Hydroxypregnenolone; Hydrocortisone | 0.06 | Up | Negative |