Table 3 KEGG pathway analysis of cord blood metabolites associated with the pre-pregnancy overweight/obeisty group versus the control group
KEGG Pathway | Screened Metabolites | P value | Trend | Mode |
|---|---|---|---|---|
Steroid hormone biosynthesis | Testosterone; 7α-Hydroxytestosterone; Cortisol; Corticosterone; Cortodoxone | 0.01 | Up | Positive |
Neuroactive ligand-receptor interaction | Cortisol; Octopamine | 0.03 | Up | Positive |
Cortisol synthesis and secretion | Cortisol; Cortodoxone | 0.08 | Up | Positive |
Cushing’s syndrome | Cortisol; Cortodoxone | 0.08 | Up | Positive |
Prostate cancer | Testosterone; Cortisol | 0.08 | Up | Positive |
Pantothenate and CoA biosynthesis | Pantothenic acid | 0.08 | Up | Positive |
Prion diseases | Corticosterone | 0.08 | Up | Positive |