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Table 2 The biochemical parameters of the mothers during pregnancy

From: The influence of maternal prepregnancy weight and gestational weight gain on the umbilical cord blood metabolome: a case–control study

 

Overweight/obesity(n = 33)

Excessive GWG (n = 30)

Control (n = 32)

The first trimester of pregnancy (8–14 weeks)

 GLU, mmol/L

4.59 ± 0.30

4.65 ± 0.27

4.57 ± 0.25

 TCHO, mmol/L

4.24 ± 0.55

4.17 (3.51, 4.40)

4.10 ± 0.76

 TG, mmol/L

1.10 (0.92, 1.75)a,b

0.95 ± 0.30

0.93 (0.72, 1.21)

 HDL-C, mmol/L

1.44 ± 0.29

1.53 ± 0.22

1.56 ± 0.25

 LDL-C, mmol/L

2.36 ± 0.62

2.12 (1.96, 2.57)

2.14 ± 0.65

 UA, μmol/L

253.6 ± 55.0a,b

212.5 ± 42.6

194.8 (176.2, 238.3)

 HCY, μmol/L

6.30 (5.70, 6.70)

6.20 (5.35, 7.90)

6.11 ± 1.21

The second trimester of pregnancy (24–28 weeks)

 OGTT

  GLU (0h), mmol/L

4.47 ± 0.26

4.47 (4.32, 4.59)

4.34 ± 0.30

  GLU (1h), mmol/L

7.52 ± 1.18

6.97 ± 1.61

7.54 ± 1.36

  GLU (2h), mmol/L

6.25 ± 0.89

6.15 ± 1.01

6.33 ± 0.99

 TCHO, mmol/L

5.60 ± 0.82

6.30 ± 1.45

6.02 ± 0.99

 TG, mmol/L

2.29 ± 0.91

2.06 ± 0.60

1.87 (1.59, 2.34)

 HDL-C, mmol/L

1.82 ± 0.28a

2.07 ± 0.39

2.04 ± 0.34

 LDL-C, mmol/L

3.05 ± 0.83

3.39 (2.84, 3.94)

3.29 ± 0.95

The third trimester of pregnancy (32–34 weeks)

 GLU, mmol/L

4.25 (4.12, 4.62)

4.42 ± 0.40

4.31 ± 0.32

 TCHO, mmol/L

6.15 ± 1.06

6.83 ± 1.37

6.77 (5.78, 7.69)

 TG, mmol/L

2.91 ± 0.96

2.43 (2.13, 3.12)

2.70 (2.40, 3.17)

 HDL-C, mmol/L

1.88 ± 0.30

1.97 ± 0.33

2.01 ± 0.38

 LDL-C, mmol/L

3.37 ± 1.04

3.58 (3.21, 4.46)

3.80 ± 1.02

 UA, μmol/L

264.0 ± 46.1

249.1 (228.7, 310.4)

244.4 ± 44.7

 HCY, μmol/L

5.10 (4.60, 5.60)

5.45 (5.10, 6.33)

5.91 ± 1.24

  1. Abbreviations: GWG gestational weight gain, GLU glucose, TCHO total cholesterol, TG triglyceride, HDL-C high density lipoprotein-cholesterol, LDL-C low density lipoprotein-cholesterol, UA uric acid, HCY homocysteine, OGTT oral glucose tolerance test
  2. aOverweight/obesity vs. excessive GWG P < 0.05
  3. bOverweight/obesity vs. control P < 0.05