Fig. 4

KEGG enrichment scatterplots (a) and net (b) of differential cord blood metabolites. A the prepregnancy overweight/obesity group vs. the control group; B the excessive GWG group vs. the control group. (1) positive metabolites; (2) negative metabolites. Notes: (a) The horizontal co-ordinates in the figure are x/y (the number of differential metabolites in the corresponding metabolic pathway/the total number of total metabolites identified in this pathway). The value represents the enrichment degree of differential metabolites in the pathway. The color of the point rep-resents the P-value of the hypergeometric test, and the size of the point represents the number of differential metabolites in the corresponding pathway. (b) The red dot represents a metabolic pathway, the yellow dot represents a substance-related regulatory enzyme information, the green dot represents the background substance of a metabolic pathway, the purple dot represents the molecular module information of a class of substances, the blue dot represents a substance chemical reaction, and the green square represents the differential substance obtained by this comparison