Comparison of the efficacy of nifedipine with ritodrine, nitroglycerine and magnesium sulfate for the management of preterm labor: a systematic review and meta-analysis

Zamani, Maryam; Alimi, Rasoul; Arabi, Seyyed Mostafa; Moradi, Maryam; Azmoude, Elham

doi:10.1186/s12884-024-06497-w

Table 1 Characteristics of the included trials comparing the efficacy of nifedipine with that of ritodrine, nitroglycerine and magnesium sulfate for the management of preterm labor

From: Comparison of the efficacy of nifedipine with ritodrine, nitroglycerine and magnesium sulfate for the management of preterm labor: a systematic review and meta-analysis

Study author’s	Publication year	Country	Intervention	Sample size	Age Mean or range			Gestational age Mean or range				Prolongation of labor More than 48 h percent (%)		Reference
Study author’s	Publication year	Country	Intervention	Sample size	N^*	NG^/R^/M^*		N	NG/R/M			N	NG/R/M
Akhtar	2020	Pakistan	N- NG	126	28.7	29.9		32.1	32.3			-	-	[49]
Badshah	2019	Pakistan	N- NG	154	29.5			Not reported				54.5	59.7	[50]
Balasubramani	2017	India	N- NG	100	23.9	24.0		28–36				22	14	[24]
Dhawle	2013	India	N- NG	84	26.2	25.8		31.3	31.1			-	-	[28]
Iftikhar	2017	Pakistan	N- NG	72	26.5			26–35						[33]
Jamil	2020	Pakistan	N- NG	100	26.0	30.4		31.2	31.4			-	-	[16]
Kashanian	2014	Iran	N- NG	120	26.0	24.0		31.4	31.5			68.3	86.7	[35]
Kaur	2021	India	N- NG	100	20–29			28–34				40	60	[36]
Khan	2019	Pakistan	N- NG	200	20–40			Not reported				58	54	[44]
Sharma	2019	India	N- NG	100	24.4	24.1		32.8			33			[40]
Zulfiqar	2016	Pakistan	N- NG	60	30.5	28.1		30.5	29.1			23.3	33.3	[43]
Padmini	2015	India	N- NG	195	Without restriction			28–36				-	-	[39]
Vinodhini	2019	India	N- NG	80	28–37			28–36				15	5	[41]
Yasmin	2016	Pakistan	N- NG	50	Not reported			28–34				8	16	[42]
Goyal	2023	India	N- NG	130	24.4		24.9	28–37				61	65	[58]
Kalburgi	2023	India	N- NG	120	24.2		24.2	28–36				70	61.67	[60]
Al-Qattan	2000	Kuwait	N- R	60	Without restriction			29.4	29			-	-	[13]
Bankatlal	2011	India	N- R	120	16–25			28–36				90	68.3	[34]
Ceyhan	2007	Turkey	N- R	135	28.9	28.6		33.2	34.0			80.8	62.9	[27]
Garcıa-Velasco	1998	Spain	N- R	52	31.2	29.4		31.2	29.4			88.4	92.3	[30]
Gurjar	2017	India	N- R	100	16–40			28–36				80	68	[32]
Kupfermi	1993	Israel	N- R	60	28.4	28.6		30.1	30.2			83	77	[47]
Maitra	2007	India	N- R	70	Not reported			Under 34				2.9	17.1	[11]
Papatsoni	1997	Netherlands	N- R	185	28.7	29.8		28.8	29.5			37	19.1	[53]
Bracero	1991	USA	N- R	42	24.0	26.0		20–36				-	-	[26]
Cararach	2005	Spain	N- R	78	26.9	26.2		32.2	32.1			-	-	[14]
DikshaAmbedkar	2022	India	N- M	200	Without restriction			24–37				9	5	[54]
Glock	1993	USA	N- M	80	21.4	20.5		30.2	30.4			92	93	[31]
Kara	2009	Turkey	N- M	76	26	24.7		31.1	30.7			84.2	87.5	[52]
Khan	2021	Pakistan	N- M	180	32	32		35			35	-	-	[45]
Klauser	2013	USA	N- M	199	22.2	23.9		28.6			28.6	-	-	[46]
Klauser	2015	USA	N- M	60	23.6	22.7		30.1			30.8	59.3	60.6	[19]
Nikbakht	2014	Iran	N- M	100	Without restriction			24–37				8	4	[37]
Niroomanesh	2001	Iran	N- M	46	25.5	23.9		33.3			33.9	91.3	78.2	[38]
Faraji	2013	Iran	N- M	100	24.4	23.8		32.6			31.6	72	48	[29]
Subhashini	2013	India	N- M	200	Without restriction			28–34				-	-	[48]
Vinodhini	2019	India	N- M	80	18–40			24–28				15	2	[41]
Alavi	2015	Iran	N- M	64	Not reported			25–34				90.6	90.6	[51]
Bhat	2023	India	N- M	80	23		25	28–37				85	80	[59]
Saleem	2023	Pakistan	N- M	178	25.9		26.4	33.1		32.5		-	-	[61]

N: Nifedipine NG: Nitroglycerin M: Magnesium sulfate R: Ritodrine

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