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Table 2 Characteristics of 15 meta-analyses included in the umbrella review

From: The maternal factors associated with infant low birth weight: an umbrella review

Risk factors

Reference (year)

No. of total population

No. of studies in meta-analyze

Study design

measure

Summary relative risk estimate (95% CI)

Credibility of evidence

AMSTAR2 quality

crack cocaine

Dos Santo, (2018)

5453

7

Case-control/cohort

OR

2.82 (2.26, 3.52)

Class I

Critically low

Infertility

Carmen ( 2013)

106,040

6

Case-control/cohort

OR

1.34 (1.20, 1.48)

Class I

Critically low

smoking

Pereira, (2017)

3,259,833

30

Case-control/cohort

OR

2.00 (1.76, 2.28)

Class II

Critically low

antenatal Care

Garedew. (2023)

6763

4

Observational follow-up/ Cross-sectional

OR

0.47 (0.37, 0.62)

Class II

Critically low

Periodontal disease

Zhan, (2022)

10,588

14

Case-control/cohort

OR

2.41 (1.67, 3.47)

Class III

Critically low

Depression

Ghimire, (2021)

35,000

12

Case-control/cohort/ cross-sectional

OR

1.84 (1.34, 2.53)

Class III

Critically low

anemia

Rahman, (2016)

237,072

17

Cohort

RR

1.32 (1.13, 1.55)

Class III

Critically low

caffeine/coffee

Feng Jin (2021)

95,612

11

Cohort

RR

1.34 (1.14, 1.57)

Class III

Critically low

heavy physical workload

Cai, (2020)

160,492

5

observational studies

OR

1.87 (1.00, 3.47)

Class IV

Critically low

underweight

Liu, (2019)

313,569

15

Cohort/cross sectional

OR

1.79 (1.20, 2.67)

Class IV

Critically low

lifting ≥ 11 kg

Cai, (2020)

18,158

5

observational studies

OR

1.59 (1.02, 2.48)

Class IV

Critically low

alcohol

Pereira, (2019)

497,023

38

Case-control/cohort

OR

1.23 (1.04, 1.46)

Class IV

Critically low

hypothyroidism

Jiatong (2016)

23,879

5

Cohort

RR

1.40 (1.01, 1.94)

Class IV

Critically low

Hypertension

Getaneh (2020)

1166

14

Case-control/cohort/ cross-sectional

OR

3.90 (2.73, 5.58)

Class IV

Critically low

overweight/obesity

Liu, (2019)

313,569

15

Cohort/cross sectional

OR

1.17 (1.00, 1.36)

NS

Critically low