Fig. 3
From: Establishment of a placental lncRNA-mRNA expression network for early-onset preeclampsia
Weighted gene co-expression network analysis (WGCNA) of all lncRNAs and mRNAs expressed in early-onset PE and control groups. A. WGCNA assigned all lncRNAs and mRNAs expressed in early-onset PE and control groups into different co-expression modules. Positive and negative values indicate modules with increased and decreased expressions respectively, in early-onset PE group compared with those in control group. Dashed lines signify associated modules. B. A boxplot of expression levels (log fold change) of mRNAs and lncRNAs of each module. C–E. The network of hub mRNAs and lncRNAs (right) and the KEGG pathways enrichment assay (left) of blue (C), tan (D), and light cyan (E) modules. Brown circles indicate hub mRNAs. Blue circles indicate hub lncRNAs