Fig. 1
From: Establishment of a placental lncRNA-mRNA expression network for early-onset preeclampsia
Identification of early-onset preeclampsia (early-onset PE)-related differentially expressed lncRNAs (DElncRNAs) in the GSE14821 dataset. (A) RNA sequencing data of the GSE148241 dataset were acquired. The workflow diagram was shown. (B) Venn diagram of lncRNAs expressed in early-onset PE and control placenta tissue samples was shown. LncRNAs with reads per kilobase of exon per million fragments mapped (RPKM) ≥ 0.2 in at least two samples were included. (C) The number of upregulated and downregulated DElncRNAs. D, E. Principal component analysis (PCA) of DElncRNAs and DEmRNAs. The samples were grouped by disease state. The ellipse indicates the 95% confidence regions of each group. F. Heatmap of DElncRNA expression in placenta samples of early-onset PE group versus control group. PE, preeclampsia; Ctrl, control