Systematic review and meta-analysis on the effect of adjuvant gonadotropin-releasing hormone agonist (GnRH-a) on pregnancy outcomes in women with endometriosis following conservative surgery

Table 2 Subgroup analysis of pregnancy rate and live birth rate

Subgroup	No. of groups	RR (95% CI)	P Value	P for heterogeneity	I² (%)	P for between Subgroup heterogeneity
Pregnancy rate					55%
GnRH-a group						0.90
Long proposal	5	1.03(0.83–1.28)	0.76	0.67	0
Short proposal	14	1.02(0.92–1.12)	0.74	1.00	0
Control group						0.56
Blank	12	0.99(0.87–1.13)	0.87	0.98	0
Other medications	7	1.05(0.93–1.18)	0.49	0.97	0
Whether ART						0.62
ART	7	1.01(0.91–1.13)	0.83	0.88	0
spontaneously	3	1.13(0.73–1.75)	0.73	0.96	0
Study quality						0.88
High quality	14	1.02(0.92–1.11)	0.74	0.99	0
Low quality	5	1.04(0.78–1.39)	0.79	0.93	0
live birth rate					79%
GnRH-a group						0.48
Long proposal	1	1.23(0.73–2.06)	0.44	NA	NA
Short proposal	6	1.01(0.88–1.16)	0.87	0.76	0
Control group						0.30
Blank	3	0.97(0.81–1.15)	0.71	0.54	7.6
Other medications	3	1.12(0.90–1.39)	0.30	0.88	0
Whether ART						0.38
ART	3	0.96(0.79–1.16)	0.65	0.55	0
spontaneously	1	1.23(0.73–2.06)	0.44	NA	NA
Study quality						0.48
High quality	6	1.01(0.88–1.16)	0.87	0.78	0
Low quality	1	1.23(0.73–2.06)	0.44	NA	NA

ISSN: 1471-2393