Table 2 Incidence of aneuploidy, pathogenic, likely pathogenic, and variants of uncertain significance CNVs in four groups of pregnant women (%)
From: The yield of SNP microarray analysis for fetal ultrasound cardiac abnormalities
| Â | n | aneuploidy | Pathogenic CNVs | Likely pathogenic CNVs | Total known pathogenic and likely pathogenic findings | variants of uncertain significance CNVs | ||
|---|---|---|---|---|---|---|---|---|
22q11.2 | Other | Total | ||||||
Isolated CHD group | 170 | 6(3.5) | 5(2.9) | 9(5.3) | 14(8.2) | 0(0) | 20(11.8) | 14(8.2) |
Non-isolated CHD group | 68 | 19(27.9) | 3(4.4) | 7(10.3) | 10(14.7) | 0(0) | 29(42.6) | 6(8.8) |
Non-CHD group | 538 | 46(8.6) | 2(0.4) | 28(5.2) | 30(5.6) | 2(0.4) | 78(14.5) | 28(5.2) |
Control group | 1316 | 78(5.9) | 5(0.4) | 37(2.8) | 42(3.2) | 3(0.4) | 123(9.3) | 41(3.1) |
P-value |  | < 0.001 | < 0.001 | 0.005 | < 0.001 |  - | < 0.001 | 0.031 |