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Table 1 Baseline characteristics of patients

From: Impact of thyroid autoimmunity on the cumulative live birth rates after IVF/ICSI treatment cycles

Characteristics

TAI group (N = 2603)

Control group (N = 10,193)

P-value

Age, mean (SD), years

32.7 (4.1)

32.4 (4.3)

0.001

BMI, mean (SD), kg/m2

22.9 (3.7)

22.8 (3.7)

0.094

Duration of infertility, median (IQR), years

3.0 (2.0–4.0)

3.0 (2.0–4.0)

0.832

Type of infertility, No. (%)

   

 Primary

1482 (56.9)

5894 (57.8)

0.412

 Secondary

1121 (43.1)

4299 (42.2)

Cause of infertility, No. (%) a

   

 Male factor only

771 (29.6)

2761 (27.1)

0.028

 Ovulation disorder

429 (16.5)

1623 (15.9)

 Tubal factor

891 (34.2)

3768 (37.0)

 Endometriosis

197 (7.6)

842 (8.3)

 Unexplained

315 (12.1)

1199 (11.8)

Basal FSH, median (IQR), mIU/mL b

6.4 (5.1–7.9)

6.3 (5.0-7.8)

0.581

Basal LH, median (IQR), mIU/mL b

3.5 (2.3–5.2)

3.6 (2.3–5.2)

0.319

Basal oestradiol, median (IQR), pmol/L b

152.0 (110.0-195.0)

152.0 (110.0-196.0)

0.917

AMH, median (IQR), ng/mL

2.6 (1.4–4.4)

2.5 (1.4–4.4)

0.317

FT4, median (IQR), ng/dL

1.3 (1.2–1.4)

1.3 (1.2–1.4)

< 0.001

TSH, median (IQR), mIU/L

2.2 (1.5-3.0)

2.0 (1.4–2.7)

< 0.001

Sperm concentration, median (IQR), million/mL

49.7 (24.9–85.2)

52.0 (26.5–86.6)

0.102

Sperm motility, median (IQR), %

28.0 (15.7–43.5)

29.0 (16.2–44.0)

0.227

  1. BMI, body mass index; FSH, follicle-stimulating hormone; LH, luteinizing hormone; AMH, anti-Müllerian hormone; FT4, free thyroxine; TSH, thyroid-stimulating hormone; COS, controlled ovarian stimulation; IQR, interquartile range; SD, standard deviation
  2. a Cause of infertility is the most important indication for couples who undergo IVF/ICSI treatment
  3. b Testing for basal FSH, LH, and oestradiol was performed between day 2 and day 4 of the menstrual cycle