Table 3 Results from logistic regression analyses of composite adverse outcome^a according to maternal, pregnancy and histologic characteristics in a prospective observational study of 315 singleton term placentas meeting the criteria for referral to histopathologic examination

Unadjusted models

Adjusted model^b

Characteristics

OR

95% CI

p-value

OR

(95% CI)

p-value

Age^c (years)

1.00

(0.95, 1.05)

0.994

BMI ≥ 30 (kg/m²)

1.24

(0.56, 2.73)

0.599

Smoking

5.34

(1.57, 18.22)

0.005

5.10

(1.48, 17.60)

0.008

Primiparity

1.20

(0.73, 1.99)

0.467

Gestation week^d

0.98

(0.83, 1.16)

0.816

Preeclampsia

0.90

(0.49, 1.65)

0.726

Clinical chorioamnionitis

2.10

(0.80, 5.50)

0.140

Pregestational diabetes

0.74

(0.20, 2.76)

0.648

Gestational diabetes

1.38

(0.53, 3.57)

0.519

PROM

0.22

(0.03, 1.70)

0.074

Histologic chorioamnionitis^e

2.19

(1.15, 4.16)

0.019

2.10

(1.09, 4.04)

0.029

Fetal inflammatory response^f

1.82

(0.99, 3.23)

0.056

Maternal vascular malperfusion

0.71

(0.43, 1.18)

0.183

Fetal vascular malperfusion

2.10

(0.91, 4.82)

0.086

Delayed villous maturation

1.27

(0.68, 2.37)

0.457