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Table 1 Characteristics of pregnant women included in this study and their infants

From: Genome-wide association study of nausea and vomiting during pregnancy in Japan: the TMM BirThree Cohort Study

 

Discovery stage

(JPA NEO)

Replication stage

(JPAv2)

n

9464

10,051

Age (years)

31.2 ± 5.0

31.2 ± 5.0

Height (cm)

158.4 ± 5.4

158.4 ± 5.3

Pre-pregnancy weight (kg)

53.5 ± 9.0

54.0 ± 9.2

Gestational age at acquisition of the NVP variable (weeks)

21.3 ± 9.7

19.6 ± 8.5

NVP

  

 No

1360 (14.4)

1439 (14.3)

 Nausea only

4144 (43.8)

4481 (44.6)

 Vomited but could eat

2897 (30.6)

3102 (30.9)

 Vomited and could not eat

1063 (11.2)

1029 (10.2)

Parity

  

 Never

4311 (45.6)

5166 (51.4)

 One or more

5142 (54.3)

4861 (48.4)

 Missing

11 (0.1)

24 (0.2)

Infant sex

  

 Male

4827 (51.0)

5200 (51.7)

 Female

4558 (48.2)

4833 (48.1)

 Missing

79 (0.8)

18 (0.2)

Gestational age at delivery

  

 < 37 weeks

592 (6.3)

559 (5.6)

 37–41 weeks

8713 (92.1)

9434 (93.9)

 ≥ 42 weeks

9 (0.1)

14 (0.1)

 Missing

150 (1.6)

44 (0.4)

HDP

  

 Yes

388 (4.1)

493 (4.9)

 No

8965 (94.7)

9530 (94.8)

 Missing

111 (1.2)

28 (0.3)

GDM

  

 Yes

239 (2.5)

228 (2.3)

 No

9114 (96.3)

9795 (97.5)

 Missing

111 (1.2)

28 (0.3)

  1. Data show means ± SD or n (%); GDM, gestational diabetes mellitus; HDP, hypertensive disorder in pregnancy; JPA NEO, Axiom Japonica Array NEO; JPAv2, Axiom Japonica Array v2; NVP, nausea and vomiting of pregnancy; SD, standard deviation