Critical congenital heart disease: contemporary prenatal screening performance and outcomes in a multi-centre perinatology service

Table 2 Prenatal ciagnoses and outcomes (N = 96)

Outcome	All (N=96)	Lt duct dependant heart (N =40)	Rt duct dependant heart (N=37)	TGA (N=16)	Congenital Heart Block(N=3)
Extracardiac structural anomaly^a	31 (32%)	16 (40%)	14 (38%)	1 (6%)	0
Genetic abnormality
T21	2 (2%)	0	2 (5%)	0	0
T18	3 (3%)	3 (8%)	0	0	0
T13	1 (1%)	1 (3%)	0	0	0
Di George	4 (4%)	1 (3%)	3 (8%)	0	0
Other^b	8 (8%)	5 (13%)	3 (8%)	0	0
Isolated CCHD	60 (63%)	22 (55%)	20 (54%)	15 (94%)	3 (100%)
Pregnancy termination	10 (10%)	8 (20%)	1 (3%)	1 (6%)	0
In-utero fetal death	7 (7%)	2 (5%)	4 (11%)	0	1 (33%)
Liveborn	79 (82%)	30 (75%)	32 (86%)	15 (94%)	2 (67%)

n (%) is presented for categorical data and mean (SD) for numeric data
^aExtra-cardiac anomalies = dysplastic kidneys, solitary kidney, polyhydramnios, Hypoplastic nasal bone, short long bones, duodenal atresia, talipes, Heterotaxy syndrome, spina bifida, echogenic bowel, agenesis of cerebellar vermis, cleft lip, TTTS, bipedal odema
^bOther genetic diagnosis + + = Alagille syndrome,47XXX, Jacobsen syndrome, del ch11q 24.3, monosomy X, copy loss Ch9, Gain Ch11, cri du chat, copy loss Ch16, deletion on Ch.X xq26.1q26.2, tetrasomy of Ch18, T16, tuberous sclerosis, unbalanced karyotype 10, mosaic ring 13 53mb deletion, microdeletion of ch 17

ISSN: 1471-2393