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Table 1 Characteristics of individual studies included in the meta-analysis

From: Can single progesterone concentration predict miscarriage in early pregnant women with threatened miscarriage: a systematic review and meta-analysis

Authors

(year)

Country

Sample

(N)

Prospective

Recruit patients

Detection of progesterone

Cut-off

ng/mL

Supplement

Data extraction

 

Outcome assessment (weeks)

Location

Age

(years)

Gestation

(weeks)

Tp

Fp

Fn

Tn

Time

Method

Kadam [21]

(2019)

India

150

Yes

Outpatient

UK

< 12

Enzyme

11

UK

41

17

4

88

< 13

Ultrasound

Kant [20]

(2015)

India

100

Yes

Outpatient

20–39

< 12

Enzyme

24

UK

16

3

5

76

20

Follow up

Ku [26]

(2015)

Singapore

119

Yes

Emergency

> 19

6–10

CL

11

UK

23

11

7

78

< 17

Follow up

LeK [24]

(2017)

Singapore

345

Yes

Emergency

> 21

6–10

CL

11

UK

46

22

24

253

16

Follow up

Jia [23]

(2018)

Singapore

118

Yes

Emergency

21–45

6–10

CL

11

Yes

10

8

5

95

< 16

Follow up

Tan [25]

(2020)

Singapore

1087

Yes

Emergency

UK

5–12

CL

11

Yes

170

70

81

766

16

Follow up

Duan [16]

(2011)

China

175

No

Outpatient

UK

4–5

Enzyme

16

Yes

51

32

16

76

Live birth

Follow up

Wei [18]

(2022)

China

141

UK

Hospitalized

22–43

5–12

CL

22

Yes

16

10

10

105

16

Follow up

Zheng [19]

(2021)

China

173

UK

Outpatient

> 20

5–6

CL

10

Yes

38

21

14

100

12

Follow up

Li [17]

(2019)

China

100

No

Outpatient

22–35

5–7

UK

10

Yes

18

10

8

64

12

Follow up

Shen [15]

(2013)

China

76

UK

Outpatient

UK

< 12

CL

30

Yes

38

7

6

25

Live birth

Follow up

McLindon [22]

(2023)

Australia

133

Yes

Outpatient

> 18

< 10

UK

8

Yes

8

2

15

108

Live birth

Follow up

128

No

4

1

17

106

133

16

Yes

17

42

6

68

128

No

14

41

7

66

  1. TP = True Positive, FP = False Positive, TN = True Negative, FN = False Negative
  2. Enzyme = Enzyme Immunoassay. CL: Chemiluminescence
  3. UK = unknown