Breast milk concentrations of acetaminophen and diclofenac - unexpectedly high mammary transfer of the general-purpose drug acetaminophen

Table 2 Data of 18 women who used acetaminophen

Patient number	Body-Mass Index (kg/m²)	acetaminophen dose (mg)	Days after delivery	Time after acetaminophen use (hr)	Plasma concentration (ng/ml)	Breast milk concentration (ng/ml)
1	19.6	500	6	15	165	186
1	19.6	500	6	23	57.5	74.3
2	24.8	500	6	10	1108	1406
3	23.2	500	6	6	677	815
4	31.3	500	6	68	2.31	2.51
5	22.2	500	6	7.5	1710	1740
6	27.7	500	6	3	3330	3970
7	28.0	500	6	5	1040	1320
8	18.9	500	6	2	10,960	11,020
9	23.0	500	6	2	4480	4840
10	29.4	500	4	1.6	4550	5590
11	28.0	500	6	2.5	3350	2770
12	27.0	500	6	12	328	305
13	26.4	500	4	2	8070	7290
13	26.4	500	4	4	3820	4120
14	20.5	500	6	6.5	2170	2460
15	21.1	500	6	0.8	11,920	13,480
16	28.7	500	6	7	1170	1170
17	28.9	500	6	4	2850	3130
18	25.7	500	6	10.5	690	643

ISSN: 1471-2393