From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study
Variables | UA, μmol/L | Total (n=69,674) | SGA (n (%)) | Crude model | Adjusted model | ||
---|---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | ||||
BMI, kg/m2 | |||||||
<25 | <360 | 59,985 | 5532(9.2) | ref | ref | ||
≥360 | 841 | 154(18.3) | 2.21(1.85,2.63) | <0.001 | 1.66(1.37,2.00) | <0.001 | |
≥25 | <360 | 6428 | 345(5.4) | 0.56(0.50,0.62) | <0.001 | 0.51(0.46,0.58) | <0.001 |
≥360 | 297 | 38(12.8) | 1.44(1.03,2.03) | 0.035 | 0.90(0.62,1.30) | 0.570 | |
missing | 2123 | ||||||
P for trend | <0.001 | <0.001 | |||||
GH | |||||||
No | <360 | 38,179 | 3079(8.1) | ref | ref | ||
≥360 | 455 | 57(12.5) | 1.63(1.23,2.16) | 0.001 | 1.70(1.27,2.28) | <0.001 | |
Yes | <360 | 7914 | 856(10.8) | 1.38(1.28,1.50) | <0.001 | 1.52(1.27,1.81) | <0.001 |
≥360 | 271 | 67(24.7) | 3.74(2.83,4.95) | <0.001 | 2.63(1.83,3.78) | <0.001 | |
missing | 22,855 | ||||||
P for trend | <0.001 | <0.001 | |||||
PE | |||||||
No | <360 | 40,999 | 3383(8.3) | ref | ref | ||
≥360 | 577 | 78(13.5) | 1.74(1.37,2.21) | <0.001 | 1.69(1.30,2.19) | <0.001 | |
Yes | <360 | 2328 | 305(13.1) | 1.68(1.48,1.90) | <0.001 | 1.11(0.90,1.37) | 0.328 |
≥360 | 144 | 45(31.2) | 5.05(3.55,7.20) | <0.001 | 1.81(1.18,2.78) | 0.007 | |
missing | 25,626 | ||||||
P for trend | <0.001 | 0.006 | |||||
DGW, weeks | |||||||
≥37 | <360 | 64,865 | 5559(8.6) | ref | ref | ||
≥360 | 1013 | 124(12.2) | 1.49(1.23,1.80) | <0.001 | 1.52(1.24,1.87) | <0.001 | |
<37 | <360 | 3584 | 517(14.4) | ref | ref | ||
≥360 | 212 | 83(39.2) | 3.82(2.85,5.11) | <0.001 | 2.13(1.50,3.02) | <0.001 |