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Table 6 Synergistic effects (LBW)

From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study

Variables

UA, μmol/L

Total (n=69,674)

LBW (n (%))

Crude model

Adjusted model

OR (95% CI)

P-value

OR (95% CI)

P-value

BMI, kg/m2

 No

<360

59,985

1768(2.9)

ref

 

ref

 

≥360

841

126(15.0)

5.80(4.77,7.05)

<0.001

2.35(1.66,3.31)

<0.001

 Yes

<360

6428

225(3.5)

1.19(1.04,1.38)

0.014

0.54(0.43,0.68)

<0.001

≥360

297

44(14.8)

5.73(4.14,7.91)

<0.001

1.10(0.60,2.02)

0.762

 missing

 

22,855

     

P for trend

    

<0.001

 

<0.001

GH

 No

<360

38,179

944(2.5)

ref

 

ref

 

≥360

455

29(6.4)

2.69(1.83,3.93)

<0.001

2.54(1.40,4.60)

0.002

 Yes

<360

7914

342(4.3)

1.78(1.57,2.02)

<0.001

2.26(1.55,3.31)

<0.001

≥360

271

73(26.9)

14.54(11.03,19.17)

<0.001

4.00(2.01,7.93)

<0.001

 missing

 

22,855

     

P for trend

    

<0.001

 

<0.001

PE

 No

<360

40,999

1068(2.6)

ref

 

ref

 

≥360

577

44(7.6)

3.09(2.26,4.22)

<0.001

2.10(1.25,3.53)

0.005

 Yes

<360

2328

167(7.2)

2.89(2.44,3.42)

<0.001

1.06(0.69,1.63)

0.775

≥360

144

58(40.3)

25.22(17.97,35.37)

<0.001

1.38(0.63,3.03)

0.418

 missing

 

25,626

     

P for trend

    

<0.001

 

0.226

DGW, weeks

 ≥37

<360

64,865

629(1.0)

ref

 

ref

 

≥360

1013

30(3.0)

3.12(2.15,4.52)

<0.001

2.46(1.62,3.73)

<0.001

 <37

<360

3584

1473(41.1)

ref

 

ref

 

≥360

212

151(71.2)

3.55(2.62,4.81)

<0.001

2.70(1.92,3.80)

<0.001

  1. Adjusted for variables: age, education, family income, ART, smoking, BMI, parity, SBP, DBP, CHOL, TG, GH, PE, Anaemia, GDM, delivery method, DGW.