From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study
Variables | UA, μmol/L | Total (n=69,674) | LBW (n (%)) | Crude model | Adjusted model | ||
---|---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | ||||
BMI, kg/m2 | |||||||
No | <360 | 59,985 | 1768(2.9) | ref | ref | ||
≥360 | 841 | 126(15.0) | 5.80(4.77,7.05) | <0.001 | 2.35(1.66,3.31) | <0.001 | |
Yes | <360 | 6428 | 225(3.5) | 1.19(1.04,1.38) | 0.014 | 0.54(0.43,0.68) | <0.001 |
≥360 | 297 | 44(14.8) | 5.73(4.14,7.91) | <0.001 | 1.10(0.60,2.02) | 0.762 | |
missing | 22,855 | ||||||
P for trend | <0.001 | <0.001 | |||||
GH | |||||||
No | <360 | 38,179 | 944(2.5) | ref | ref | ||
≥360 | 455 | 29(6.4) | 2.69(1.83,3.93) | <0.001 | 2.54(1.40,4.60) | 0.002 | |
Yes | <360 | 7914 | 342(4.3) | 1.78(1.57,2.02) | <0.001 | 2.26(1.55,3.31) | <0.001 |
≥360 | 271 | 73(26.9) | 14.54(11.03,19.17) | <0.001 | 4.00(2.01,7.93) | <0.001 | |
missing | 22,855 | ||||||
P for trend | <0.001 | <0.001 | |||||
PE | |||||||
No | <360 | 40,999 | 1068(2.6) | ref | ref | ||
≥360 | 577 | 44(7.6) | 3.09(2.26,4.22) | <0.001 | 2.10(1.25,3.53) | 0.005 | |
Yes | <360 | 2328 | 167(7.2) | 2.89(2.44,3.42) | <0.001 | 1.06(0.69,1.63) | 0.775 |
≥360 | 144 | 58(40.3) | 25.22(17.97,35.37) | <0.001 | 1.38(0.63,3.03) | 0.418 | |
missing | 25,626 | ||||||
P for trend | <0.001 | 0.226 | |||||
DGW, weeks | |||||||
≥37 | <360 | 64,865 | 629(1.0) | ref | ref | ||
≥360 | 1013 | 30(3.0) | 3.12(2.15,4.52) | <0.001 | 2.46(1.62,3.73) | <0.001 | |
<37 | <360 | 3584 | 1473(41.1) | ref | ref | ||
≥360 | 212 | 151(71.2) | 3.55(2.62,4.81) | <0.001 | 2.70(1.92,3.80) | <0.001 |