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Table 4 Logistic regression analysis of UA and LBW

From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study

UA, μmol/L

Total(n=69,674)

LBW (n (%))

Crude model

Adjusted model

OR (95% CI)

P-value

OR (95% CI)

P-value

Total

 Q1(<213.8)

17,391

504(2.9)

ref

 

ref

 

 Q2(213.8-242.0)

17,362

477(2.7)

0.95(0.83,1.07)

0.397

1.10(0.91,1.33)

0.315

 Q3(242.0-273.5)

17,467

524(3.0)

1.04(0.92,1.17)

0.574

1.33(1.11,1.60)

0.002

 Q4(≥273.5)

17,454

778(4.5)

1.56(1.39,1.75)

<0.001

1.57(1.31,1.87)

<0.001

P for trend

   

<0.001

 

0.001

First trimester

 Q1(<180.0)

14,588

374(2.6)

ref

 

ref

 

 Q2(180.0-205.0)

14,435

419(2.9)

1.14(0.99,1.31)

0.077

1.10(0.90,1.34)

0.355

 Q3(205.0-234.0)

14,868

484(3.3)

1.28(1.12,1.47)

<0.001

1.18(0.97,1.43)

0.096

 Q4(≥234.0)

14,733

551(3.7)

1.48(1.29,1.69)

<0.001

1.02(0.83,1.24)

0.871

P for trend

   

<0.001

 

0.76

Second trimester

 Q1(<194.0)

10,823

320(3.0)

ref

 

ref

 

 Q2(194.0-222.0)

11,033

344(3.1)

1.06(0.90,1.23)

0.487

0.95(0.77,1.18)

0.655

 Q3(222.0-253.0)

11,105

388(3.5)

1.19(1.02,1.38)

0.025

1.07(0.86,1.32)

0.545

 Q4(≥253.0)

11,084

486(4.4)

1.51(1.30,1.74)

<0.001

1.02(0.83,1.27)

0.837

P for trend

   

<0.001

 

0.589

Third trimester

 Q1(<227.5)

17,064

502(2.9)

ref

 

ref

 

 Q2(227.5-261.3)

17,055

433(2.5)

0.86(0.75,0.98)

0.023

1.17(0.97,1.42)

0.095

 Q3(261.3-299.0)

17,081

464(2.7)

0.92(0.81,1.05)

0.209

1.34(1.11,1.61)

0.002

 Q4(≥299.0)

17,069

745(4.4)

1.51(1.34,1.69)

<0.001

1.79(1.50,2.14)

<0.001

P for trend

   

<0.001

 

<0.001

  1. Adjusted for variables: age, education, family income, ART, smoking, BMI, parity, SBP, DBP, CHOL, TG, GH, PE, Anaemia, GDM, delivery method, DGW