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Table 3 Logistic regression analysis of UA variation and SGA

From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study

UA variation, μmol/L

Total(n=69,674)

SGA (n (%))

Crude model

Adjusted model

OR (95% CI)

P-value

OR (95% CI)

P-value

Third-First

 Q1(<8.92)

17,060

1333(7.8)

ref

 

ref

 

 Q2(8.92-19.0)

17,017

1377(8.1)

1.04(0.96,1.12)

0.342

1.10(1.01,1.19)

0.023

 Q3(19.0-30.5)

16,898

1462(8.7)

1.12(1.03,1.21)

0.005

1.16(1.07,1.26)

<0.001

 Q4(≥30.5)

17,294

1965(11.4)

1.51(1.41,1.63)

<0.001

1.45(1.34,1.56)

<0.001

 missing

1405

     

P for trend

   

<0.001

 

0.001

Second-First

 Q1(<-34.7)

11,000

1271(11.6)

ref

 

ref

 

 Q2(-34.7-18.3)

11,022

976(8.9)

0.74(0.68,0.81)

<0.001

0.78(0.72,0.86)

<0.001

 Q3(-18.3-3.25)

10,887

903(8.3)

0.69(0.63,0.76)

<0.001

0.73(0.67,0.81)

<0.001

 Q4(≥-3.25)

11,136

918(8.2)

0.69(0.63,0.75)

<0.001

0.71(0.65,0.78)

<0.001

 missing

25,629

     

P for trend

   

<0.001

 

<0.001

Third-Second

 Q1(<15.5)

10,930

838(7.7)

ref

 

ref

 

 Q2(15.5-39.0)

10,871

943(8.7)

1.14(1.04,1.26)

0.007

1.18(1.07,1.30)

0.001

 Q3(39.0-66.0)

11,070

941(8.5)

1.12(1.02,1.23)

0.023

1.14(1.03,1.26)

0.009

 Q4(≥66.0)

11,126

1340(12.0)

1.65(1.51,1.81)

<0.001

1.56(1.42,1.71)

<0.001

 missing

25,677

     

P for trend

   

<0.001

 

<0.001

  1. Adjusted for variables: age, education, family income, ART, smoking, BMI, parity, SBP, DBP, CHOL, TG, GH, PE, Anaemia, GDM, delivery method, DGW
  2. Third-First: UA levels variation between the third and first trimester. Second-First: UA levels variation between the second and first trimester. Third-Second: UA levels variation between the third and second trimester