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Table 2 Logistic regression analysis of UA variation and LBW

From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study

UA variation, μmol/L

Total(n=69,674)

LBW (n (%))

Crude model

Adjusted model

OR (95% CI)

P-value

OR (95% CI)

P-value

Third-First

 Q1(<8.92)

17,060

627(3.7)

ref

 

ref

 

 Q2(8.92-19.0)

17,017

379(2.2)

0.60(0.52,0.68)

<0.001

1.05(0.87,1.26)

0.614

 Q3(19.0-30.5)

16,898

411(2.4)

0.65(0.58,0.74)

<0.001

1.30(1.08,1.56)

0.005

 Q4(≥30.5)

17,294

727(4.2)

1.15(1.03,1.28)

0.012

1.87(1.57,2.21)

<0.001

 missing

1405

     

P for trend

   

0.002

 

<0.001

Second-First

 Q1(<-34.7)

11,000

474(4.3)

ref

 

ref

 

 Q2(-34.7-18.3)

11,022

298(2.7)

0.62(0.53,0.72)

<0.001

0.68(0.55,0.83)

<0.001

 Q3(-18.3-3.25)

10,887

308(2.8)

0.65(0.56,0.75)

<0.001

0.56(0.45,0.69)

<0.001

 Q4(≥-3.25)

11,136

458(4.1)

0.95(0.84,1.09)

0.467

0.55(0.45,0.68)

<0.001

 missing

25,629

     

P for trend

   

0.582

 

<0.001

Third-Second

 Q1(<15.5)

10,930

443(4.1)

ref

 

ref

 

 Q2(15.5-39.0)

10,871

264(2.4)

0.59(0.50,0.69)

<0.001

0.98(0.78,1.24)

0.893

 Q3(39.0-66.0)

11,070

279(2.5)

0.61(0.53,0.71)

<0.001

1.30(1.04,1.62)

0.021

 Q4(≥66.0)

11,126

513(4.6)

1.14(1.00,1.30)

0.042

1.95(1.59,2.39)

<0.001

 missing

25,677

     

P for trend

   

0.02

 

<0.001

  1. Adjusted for variables: age, education, family income, ART, smoking, BMI, parity, SBP, DBP, CHOL, TG, GH, PE, Anaemia, GDM, delivery method, DGW
  2. Third-First: UA levels variation between the third and first trimester. Second-First: UA levels variation between the second and first trimester. Third-Second: UA levels variation between the third and second trimester