From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study
Total (n = 69,674) | Group | P-value | ||
---|---|---|---|---|
UA < 360 μmol/L (n = 68,449) | UA ≥ 360 μmol/L (n = 1225) | |||
Age, years | 31.3 ± 4.0 | 31.3 ± 4.0 | 31.3 ± 4.4 | 0.588 |
Education | < 0.001 | |||
Undergraduate and beyond | 48,576(69.7) | 47,851(69.9) | 725(59.2) | |
Below undergraduate | 21,098(30.3) | 20,598(30.1) | 500(40.8) | |
Family income, thousand | 0.008 | |||
< 100 | 2062(3.0) | 2019(2.9) | 43(3.5) | |
100–200 | 6729(9.7) | 6582(9.6) | 147(12.0) | |
200–300 | 10,032(14.4) | 9840(14.4) | 192(15.7) | |
> 300 | 10,217(14.7) | 10,059(14.7) | 158(12.9) | |
Missing | 40,634(58.3) | 39,949(58.4) | 685(55.9) | |
ART | < 0.001 | |||
No | 7858(11.3) | 7605(11.1) | 253(20.7) | |
Yes | 61,816(88.7) | 60,844(88.9) | 972(79.3) | |
Smoking (Before pregnancy) | 0.016 | |||
No | 69,267(99.4) | 68,056(99.4) | 1211(98.9) | |
Yes | 407(0.6) | 393(0.6) | 14(1.1) | |
BMI (Before pregnancy), kg/m2 | < 0.001 | |||
< 18.5 | 9000(12.9) | 8904(13.0) | 96(7.8) | |
18.5–24.9 | 51,826(74.4) | 51,081(74.6) | 745(60.8) | |
25–29.9 | 5911(8.5) | 5672(8.3) | 239(19.5) | |
> 30 | 814(1.2) | 756(1.1) | 58(4.7) | |
Missing | 2123(3.0) | 2036(3.0) | 87(7.1) | |
Parity | < 0.001 | |||
nulliparous | 48,644(69.8) | 47,703(69.7) | 941(76.8) | |
Multiparous | 21,030(30.2) | 20,746(30.3) | 284(23.2) | |
SBP, mm Hg | 119.97 ± 18.77 | 119.87 ± 18.81 | 125.62 ± 15.48 | < 0.001 |
DBP, mm Hg | 75.00 ± 9.42 | 74.93 ± 9.37 | 79.16 ± 11.15 | < 0.001 |
UA, μmol/L | 245.65 ± 47.36 | 243.02 ± 43.23 | 392.71 ± 33.82 | < 0.001 |
CHOL, mmol/L | < 0.001 | |||
< 6.22 | 62,222(89.3) | 61,177(89.4) | 1045(85.3) | |
≥ 6.22 | 7452(10.7) | 7272(10.6) | 180(14.7) | |
TG, mmol/L | < 0.001 | |||
< 2. 32 | 48,033(68.9) | 47,400(69.2) | 633(51.7) | |
≥ 2. 32 | 21,641(31.1) | 21,049(30.8) | 592(48.3) | |
GH | < 0.001 | |||
No | 38,634(55.4) | 38,179(55.8) | 455(37.1) | |
Yes | 8185(11.7) | 7914(11.6) | 271(22.1) | |
Missing | 22,855(32.8) | 22,356(32.7) | 499(40.7) | |
PE | < 0.001 | |||
No | 41,576(59.7) | 40,999(59.9) | 577(47.1) | |
Yes | 2472(3.5) | 2328(3.4) | 144(11.8) | |
Missing | 25,626(36.8) | 25,122(36.7) | 504(41.1) | |
Anemia | 0.041 | |||
No | 68,605(98.5) | 67,408(98.5) | 1197(97.7) | |
Yes | 1069(1.5) | 1041(1.5) | 28(2.3) | |
GDM | < 0.001 | |||
No | 56,590(83.8) | 55,786(84.0) | 804(71.8) | |
Yes | 10,919(16.2) | 10,603(16.0) | 316(28.2) | |
Delivery method | < 0.001 | |||
Caesarean | 31,195(44.8) | 30,454(44.5) | 741(60.5) | |
forceps | 3208(4.6) | 3161(4.6) | 47(3.8) | |
vaginal | 35,271(50.6) | 34,834(50.9) | 437(35.7) | |
Birthweight, g | < 0.001 | |||
< 1000 | 52(0.1) | 40(0.1) | 12(1.0) | |
1000–1500 | 256(0.4) | 217(0.3) | 39(3.2) | |
< 2500 | 1975(2.8) | 1845(2.7) | 130(10.6) | |
2500–4000 | 63,759(91.5) | 62,791(91.7) | 968(79.0) | |
≥ 4000 | 3632(5.2) | 3556(5.2) | 76(6.2) | |
Birthweight | < 0.001 | |||
SGA | 6283(9.0) | 6076(8.9) | 207(16.9) | |
AGA | 59,028(84.7) | 58,094(84.9) | 934(76.2) | |
LGA | 4363(6.3) | 4279(6.3) | 84(6.9) | |
DGW, weeks | < 0.001 | |||
< 37 | 3796(5.4) | 3584(5.2) | 212(17.3) | |
≥ 37 | 65,878(94.6) | 64,865(94.8) | 1013(82.7) |