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Table 1 Basic characteristics of study population

From: Association of maternal serum uric acid levels with LBW/SGA: a large retrospective cohort study

 

Total (n = 69,674)

Group

P-value

UA < 360 μmol/L

(n = 68,449)

UA ≥ 360 μmol/L

(n = 1225)

Age, years

31.3 ± 4.0

31.3 ± 4.0

31.3 ± 4.4

0.588

Education

   

 < 0.001

Undergraduate and beyond

48,576(69.7)

47,851(69.9)

725(59.2)

 

Below undergraduate

21,098(30.3)

20,598(30.1)

500(40.8)

 

Family income, thousand

   

0.008

 < 100

2062(3.0)

2019(2.9)

43(3.5)

 

100–200

6729(9.7)

6582(9.6)

147(12.0)

 

200–300

10,032(14.4)

9840(14.4)

192(15.7)

 

 > 300

10,217(14.7)

10,059(14.7)

158(12.9)

 

Missing

40,634(58.3)

39,949(58.4)

685(55.9)

 

ART

   

 < 0.001

No

7858(11.3)

7605(11.1)

253(20.7)

 

Yes

61,816(88.7)

60,844(88.9)

972(79.3)

 

Smoking (Before pregnancy)

   

0.016

No

69,267(99.4)

68,056(99.4)

1211(98.9)

 

Yes

407(0.6)

393(0.6)

14(1.1)

 

BMI (Before pregnancy), kg/m2

   

 < 0.001

 < 18.5

9000(12.9)

8904(13.0)

96(7.8)

 

18.5–24.9

51,826(74.4)

51,081(74.6)

745(60.8)

 

25–29.9

5911(8.5)

5672(8.3)

239(19.5)

 

 > 30

814(1.2)

756(1.1)

58(4.7)

 

Missing

2123(3.0)

2036(3.0)

87(7.1)

 

Parity

   

 < 0.001

nulliparous

48,644(69.8)

47,703(69.7)

941(76.8)

 

Multiparous

21,030(30.2)

20,746(30.3)

284(23.2)

 

SBP, mm Hg

119.97 ± 18.77

119.87 ± 18.81

125.62 ± 15.48

 < 0.001

DBP, mm Hg

75.00 ± 9.42

74.93 ± 9.37

79.16 ± 11.15

 < 0.001

UA, μmol/L

245.65 ± 47.36

243.02 ± 43.23

392.71 ± 33.82

 < 0.001

CHOL, mmol/L

   

 < 0.001

 < 6.22

62,222(89.3)

61,177(89.4)

1045(85.3)

 

 ≥ 6.22

7452(10.7)

7272(10.6)

180(14.7)

 

TG, mmol/L

   

 < 0.001

 < 2. 32

48,033(68.9)

47,400(69.2)

633(51.7)

 

 ≥ 2. 32

21,641(31.1)

21,049(30.8)

592(48.3)

 

GH

   

 < 0.001

No

38,634(55.4)

38,179(55.8)

455(37.1)

 

Yes

8185(11.7)

7914(11.6)

271(22.1)

 

Missing

22,855(32.8)

22,356(32.7)

499(40.7)

 

PE

   

 < 0.001

No

41,576(59.7)

40,999(59.9)

577(47.1)

 

Yes

2472(3.5)

2328(3.4)

144(11.8)

 

Missing

25,626(36.8)

25,122(36.7)

504(41.1)

 

Anemia

   

0.041

No

68,605(98.5)

67,408(98.5)

1197(97.7)

 

Yes

1069(1.5)

1041(1.5)

28(2.3)

 

GDM

   

 < 0.001

No

56,590(83.8)

55,786(84.0)

804(71.8)

 

Yes

10,919(16.2)

10,603(16.0)

316(28.2)

 

Delivery method

   

 < 0.001

Caesarean

31,195(44.8)

30,454(44.5)

741(60.5)

 

forceps

3208(4.6)

3161(4.6)

47(3.8)

 

vaginal

35,271(50.6)

34,834(50.9)

437(35.7)

 

Birthweight, g

   

 < 0.001

 < 1000

52(0.1)

40(0.1)

12(1.0)

 

1000–1500

256(0.4)

217(0.3)

39(3.2)

 

 < 2500

1975(2.8)

1845(2.7)

130(10.6)

 

2500–4000

63,759(91.5)

62,791(91.7)

968(79.0)

 

 ≥ 4000

3632(5.2)

3556(5.2)

76(6.2)

 

Birthweight

   

 < 0.001

SGA

6283(9.0)

6076(8.9)

207(16.9)

 

AGA

59,028(84.7)

58,094(84.9)

934(76.2)

 

LGA

4363(6.3)

4279(6.3)

84(6.9)

 

DGW, weeks

   

 < 0.001

 < 37

3796(5.4)

3584(5.2)

212(17.3)

 

 ≥ 37

65,878(94.6)

64,865(94.8)

1013(82.7)

 
  1. Abbreviations:ART assisted reproductive technology, BMI body mass index (calculated as weight in kilograms divided by height in meters squared), SBP systolic blood pressure, DBP diastolic blood pressure, UA uric acid, CHOL cholesterol, TG triglyceride, GH gestational hypertension, PE preeclampsia, GDM gestational diabetes mellitus, SGA small for gestational age, AGA appropriate for gestational age, LGA large for gestational age, DGW delivery gestational week