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Table 1 Basic characteristics and potential risk factors of the study participants in the two study groups

From: Incidence, risk factors and maternal outcomes of unsuspected placenta accreta spectrum disorders: a retrospective cohort study

Characteristics and potential risk factors

sPAS(219)

uPAS(120)

p value

Present conditions

Advanced maternal age

59(26.9)

27(22.5)

0.369a

Pre-pregnancy BMI

21.5 ± 3.2

21.2 ± 2.5

0.326b

Gravidity

4(3–5)

3(2–5)

0.004c

Gravidity > 3

137(62.6)

52(43.3)

< 0.001a

Parity

1(1–2)

1(1–2)

0.122c

Parity > 1

76(34.7)

35(29.2)

0.299a

Nulliparous women

6(2.7)

10(8.3)

0.020a

Multiple gestation

10(4.6)

8(6.7)

0.409a

In vitro fertilization

9(4.1)

8(6.7)

0.302a

Placenta previa

203(92.7)

85(70.8)

< 0.001a

Placenta location

  

< 0.001a

 Anterior

145(66.2)

34(28.3)

 Posterior

57(26.0)

78(65.0)

 bilateral/fundal

17(7.8)

8(6.7)

Pregnancy complications

35(16.0)

11(9.2)

0.080a

Adenomyosis/current fibroids

10(4.6)

6(5.0)

0.857a

Mullerian anomaly

3(1.4)

3(2.5)

0.670d

Severity of invasion

  

< 0.001a

 Noninvasive (accreta)

56(25.6)

89(74.2)

 Invasive (increta/percreta)

163(74.4)

31(25.8)

Delivery mode

  

< 0.001d

 Vaginal/operative vaginal

0(0)

4(3.3) e

 Planed CD

217(99.1)

81(67.5)

 Emergency CD

2(0.9)

35(29.2)

Delivery gestational weeks

35.0(34.2–35.5)

37.4(35.5–39.1)

< 0.001c

Previous conditions

History of previous CD

189(86.3)

79(65.8)

< 0.001a

History of clinical confirmed PAS

14(6.4)

25(20.8)

< 0.001a

History of endometrial ablation

1(0.5)

2(1.7)

0.287d

Previous uterine artery embolization for PPH

7(3.2)

6(5.0)

0.395d

History of myomectomy

0(0.0)

2(0.9)

NA

History of operative hysteroscopy

8(3.7)

10(8.3)

0.066a

History of intrauterine adhesions (IUA)

7(3.2)

13(10.8)

0.004a

Dilation and evacuation of the uterus

17(7.8)

12(10.0)

0.481a

History of placenta previa

11(5.0)

11(9.2)

0.139a

Previous manual removal of placenta/placenta retention

8(3.7)

12(10.0)

0.018a

  1. Data are presented as mean ± standard deviation or median (interquartile range) or n (percentage)
  2. BMI, body mass index; CD, Cesarean delivery; PAS, placenta accreta spectrum; PPH, postpartum haemorrhage; sPAS, suspected placenta accreta spectrum before delivery; uPAS, unsuspected placenta accreta spectrum before delivery
  3. a Chi-square test; b Two-sample t-test; c Wilcoxon rank-sum test; d Fisher exact test
  4. e All these cases were performed hysterectomy after vaginal delivery