Table 3 Bonferroni threshold significant results for IEU-GWAS-R PheWAS of rs9989237
From: Maternal plasma cortisol’s effect on offspring birth weight: a Mendelian Randomisation study
Trait | N | Units | Per trait raising allele effect size | Per trait raising allele standard error | P |
|---|---|---|---|---|---|
Albumin levels (inverse rank normalized transformed) | 315268 | Quantiles | -0.03354 | 0.00302 | 1.18E-28 |
Albumin levels | 315268 | g/L | -0.08683 | 0.00789 | 3.63E-28 |
SERPINA1 RNA expression in whole blood | 29950 | Z-score matrices | 0.123405 | 0.014223 | 4.09E-18 |
Expression of 39S ribosomal protein L33, mitochondrial | 3301 | Relative concentration | 0.2515 | 0.0298 | 2.82E-17 |
Expression of PH and SEC7 domain-containing protein 1 | 3301 | Relative concentration | 0.1998 | 0.0299 | 2.24E-11 |
Expression of Synaptosomal-associated protein 25 | 3301 | Relative concentration | -0.18 | 0.0299 | 1.78E-09 |
Histidine levels | 114895 | Z-scores | 0.026138 | 0.005102 | 3.00E-07 |
Sex hormone-binding globulin levels adjusted for BMI | 368929 | Log-transformed nmol/l | -0.00535 | 0.00103 | 3.40E-07 |
Sex hormone-binding globulin levels (male only GWAS) | 180726 | Log-transformed nmol/l | -0.00772 | 0.001513 | 6.60E-07 |
Sex hormone-binding globulin levels | 370125 | Log-transformed nmol/l | -0.00515 | 0.001147 | 1.70E-06 |
Sex hormone-binding globulin levels adjusted for BMI (male only GWAS) | 180094 | Log-transformed nmol/l | -0.00712 | 0.001419 | 2.30E-06 |