Table 2 The karyotyping, clinical cycle, and prenatal diagnosis of couples carrying complex-BCR

Case 1

46, XX, der(6)(6qter → 6q23.3::6p12 → 6q11::11p11.2 → 11pter, der(11)(6pter → 6p12::6q23.3 → 6q11::11p11.2 → 11qter)

GnRH antagonist

6/24

3

yes

CMA (-) monochorionic twins, healthy

Case 2

46,XX,t(12;22;15)(p10;p10;q10)

GnRH antagonist

9/36

4

yes

CMA (-) singleton, healthy

Case 3

45, XX, der(13;14)(q10;q10)t(13;18)(q13;q22)

GnRH antagonist

3/4

0

N/A

/

Case 4

45, XX, der(13;14) (q10;q10);t(5;16)(q24;p13.1)

GnRH antagonist

2/10

1

yes

CMA (-); 46, X?,t(15;16)(q24;p13.1)mat, singleton, healthy

Case 5

46, XX, inv(2) (p12p22)t(15;22)(q15;q11.2)

GnRH antagonist

3/9

2

yes

CMA (-) singleton, healthy

Case 6

46,XX,t(1;6)(p31.1;q16.1);inv(6)(p21.3q16.1)

GnRH antagonist

4/9

1

yes

/

long agonist

7/15

4

yes

CMA (-) singleton, healthy

Case 7

46,XY, inv(5)(q11.2q22)t(5;8)(q22;q11.2)

GnRH antagonist

5/15

3

yes

CMA + karyotyping (-) singleton, healthy