Skip to main content

Table 2 Univariate and multivariate analysis of factors influencing maternal mortality at 72 h postpartum

From: Factors and a model to predict three-month mortality in patients with acute fatty liver of pregnancy from two medical centers

Variables

Alive(n = 67)

Dead(n = 11)

Univariate Analysis

Multivariate Analysis

HR (95% CI)

P(< 0.10)

HR (95% CI)

P(< 0.10)

Age (years)

26.95 ± 5.91

25.73 ± 3.85

0.97(0.87–1.07)

0.47

  

Gestational age (weeks)

35.48 ± 2.66

35.90 ± 2.75

1.05(0.81–1.35)

0.72

0.85(0.63–1.15)

0.30

Multiparity

24

2

0.42(0.09–1.92)

0.26

  

Twin pregnancy

22

3

0.79(0.21–2.99)

0.73

1.47(0.15–14.43)

0.74

Perinatal death

12

2

1.04(0.22–4.80)

0.96

0.26(0.02–3.05)

0.29

Referral after delivery

21

4

1.18(0.35–4.02)

0.79

  

Vaginal delivery

18

0

0.03(0.00-8.21)

0.22

  

Postpartum hemorrhage

24

5

1.53(0.47–5.01)

0.48

1.71(0.28–10.54)

0.57

Hepatic encephalopathy

15

6

3.59(1.10-11.77)

0.04

2.88(0.43–19.53)

0.28

artificial liver supporta

14

2

0.47(0.06–3.64)

0.47

0.12(0.01–1.25)

0.08

USSb

40

9

0.92(0.20–4.26)

0.92

  

INR

1.78 ± 0.67

2.33 ± 0.86

1.99(1.15–3.44)

0.01

3.45(1.32–8.97)

0.01

Total bilirubin (µmol/l)

185.44 ± 114.95

266.66 ± 166.16

1.01(1.00-1.01)

0.04

1.01(1.00-1.01)

0.06

ALT(U/L)

83.46 ± 127.01

41.22 ± 14.80

0.98(0.95–1.01)

0.12

  

AST(U/L)

85.44 ± 108.62

79.11 ± 37.40

1.00(0.99–1.01)

0.88

  

Creatinine (µmol/l)

171.79 ± 110.76

263.32 ± 106.77

1.00(1.00-1.01)

0.02

1.01(1.00-1.01)

0.02

Serum sodium (mmol/l)

135.11 ± 5.47

134.07 ± 10.03

0.97(0.89–1.06)

0.53

  

Serum calcium(mmol/l)

1.92 ± 0.17

1.90 ± 0.24

0.70(0.03–19.08)

0.83

  

WBC count (×109/l)

20.22 ± 7.16

21.06 ± 6.21

1.01(0.93–1.10)

0.74

  

haemoglobin (g/l)

86.83 ± 18.81

85.45 ± 26.30

1.00(0.97–1.03)

0.81

  

platelet (×109/l)

99.49 ± 61.39

58.64 ± 23.20

0.98(0.96 − 1.00)

0.02

0.96(0.93-1.00)

0.04

Haematocrit (%)

26.16 ± 5.24

25.45 ± 7.33

0.98(0.87–1.09)

0.69

  

Serum glucose (mmol/l)

4.50 ± 2.25

5.32 ± 1.75

1.06(0.82–1.36)

0.68

  

BUN(mmol/L)

11.77 ± 6.84

13.94 ± 7.99

1.03(0.96–1.12)

0.40

  

Ammonia (µmol/l)

46.52 ± 25.18

52.48 ± 25.15

1.01(0.99–1.03)

0.40

  

Urate (µmol/l)

429.61 ± 196.53

529.22 ± 329.80

1.00(1.00–1.00)

0.17

  

ALP(U/L)

306.43 ± 193.63

302.37 ± 271.53

1.00(1.00–1.00)

0.89

  

LDH(U/L)

651.38 ± 432.54

777.49 ± 697.83

1.00(1.00–1.00)

0.56

  

Lactate(mmol/l)c

3.01 ± 2.34

5.79 ± 3.11

1.40(1.03–1.91)

0.04

  
  1. Continuous variables are shown as mean ± standard deviation (SD). HR: hazard ratio, CI: confidence interval; USS: Ascites or bright liver on ultrasound scan, INR: international normalised ratio, BUN: blood urea nitrogen, WBC:white blood cell count, PLT:platelet counts, ALT: Alanine Transaminase, AST: Aspartate Aminotransferase, ALP: Alkaline Phosphatase, LDH: lactate dehydrogenase
  2. Notes: a A total of 55 patients were identified as severe cases, artificial liver support was exclusively analyzed within these 55 patients
  3. b There were 48 alive cases and 11 dead cases received ultrasound scan
  4. c There were 18 alive cases and 5 dead cases monitored the blood lactate level