Fig. 6

SHAP Summary Plot for Variable Importance. The x-axis demonstrates Shapley values (impact on the model output and direction). Positive values contribute to increasing the chances of FIRS, while negative values contribute to decreasing it. On the y-axis, the predictors (IL-6, TNF-α, suPAR, MMP-8, and gestational age) are listed in descending order of their importance in the Random Forest model. The colors represent the feature values of predictors: higher values are in yellow, and lower values are in dark purple. suPAR, soluble urokinase plasminogen activator receptor; MMP-8, matrix metalloproteinase-8; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; GA, gestational age; FIRS, fetal inflammatory response syndrome