Fig. 3

The correlation matrix of suPAR levels with other inflammatory biomarkers and maternal and neonatal parameters. In the matrix, each circle indicates the correlation between two variables. Blue represents positive correlations, and red signifies negative correlations, with color intensity and circle size reflecting the strength of correlation coefficients. The legend on the right displays correlation coefficients alongside their respective colors. The correlation coefficients and P values among variables are as follows: suPAR and MMP-8 (ρ = 0.71, P < 0.001); suPAR and umbilical IL-6 (ρ = 0.22, P = 0.05); suPAR and amniotic fluid IL-6 (ρ = 0.42, P < 0.001); suPAR and TNF-α (ρ = 0.54, P < 0.001); suPAR and maternal age (ρ = -0.10, P = 0.31); suPAR and maternal C-reactive protein (ρ = 0.39, P < 0.001); suPAR and maternal white blood cell count (ρ = 0.21, P = 0.04); suPAR and gestational age (ρ = -0.29, P = 0.01); suPAR and birthweight (ρ = -0.25, P = 0.01). suPAR, soluble urokinase plasminogen activator receptor; MMP-8, matrix metalloproteinase-8; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; CRP, C-reactive protein; WBC, white blood cells