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Table 9 Samples of each group stratified and grouped according to the degree of methylation

From: Association between single nucleotide polymorphisms, TGF-β1 promoter methylation, and polycystic ovary syndrome

Group

PCOS

NORMAL

p-value

Hypomethylation

Hypermethylation

Methylation rates

85.00 − 90%

90.00 − 100.00%

90.00-100.00%

-

Number (N)

5

26

28

-

Age

27.0 ± 3.5 a

28.3 ± 3.2a

31.7 ± 4.2b

0.002

BMI

21.88 ± 4.51 a, b

22.66 (2.88) a

20.68 ± 2.40b

0.028

T (nmol/L)

1.15 ± 0.26 a

1.69 ± 0.63b

1.06 ± 0.42a

< 0.001

Fasting plasma glucose (mmol/l)

5.20(0.63)

5.04 ± 0.65

5.05 ± 0.66

0.992

Fasting insulin (uU/ml)

13.20 (18.00) a, b

11.55 (4.20) a

9.56 ± 2.90b

0.002

Homa-IR

4.03 ± 3.00 a, b

2.53 (0.58) a

2.28 (0.85) b

0.008