Association between single nucleotide polymorphisms, TGF-β1 promoter methylation, and polycystic ovary syndrome

Table 4 Number of different types of SNP in this family

Sample	synonymous SNP^a	missense SNP^b	stopgain^c	stoploss^d	unknown
II-5	11,107	10,021	77	10	450
II-2	11,089	9,995	73	11	424
I-2	11,041	10,041	70	10	460
III-3	11,026	10,001	68	8	436

^a The amino acids encoded by the mutation sites did not change. ^b The amino acids encoded by the mutation site changed, which was a non-synonymous mutation. ^c Substitution of a base causes the codon in which the base resides to become a stop codon. ^d Substitution of a base causes the termination codon in which the base resides to become a non-termination codon

ISSN: 1471-2393