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Table 2 Outcomes of infants exposed to different courses of ANS

From: Association of antenatal corticosteroids with mortality and morbidities in very preterm infants born to women with hypertensive disorders of pregnancy: a multicenter prospective cohort study

 

Complete ANS

Partial ANS

Repeat ANS

No ANS

P

N = 987

N = 560

N = 100

N = 270

Resuscitation

602(61.0)

350(62.5)

58(58)

167(61.9)

0.834

Intubation in DR

248(25.1)

164(29.3)

26(26.0)

87(32.2)

0.078

PS

398(40.3)

245(43.8)

31(31)

107(39.6)

0.101

PS ≥ 2 times

106(10.7)

71(12.7)

10(10.0)

27(10)

0.577

Hyperglycemia

77(7.8)

49(8.8)

5(5.0)

15(5.6)

0.299

Hypoglycemia

151(15.3)

67(12.0)

15(15.0)

45(16.7)

0.216

Ventilation days/length of stay

0(0,115)

0(0,128)

0(0,82)

19(0,125)

0.274

Oxygen therapy days/length of stay

347(126,706)

386(139,717)

263(29,540)

304(104,639)

0.043

Pneumothorax

8(1.1)

4(1.0)

2(3.3)

5(2.6)

0.231

Pulmonary hemorrhage

46(14.7)

35(6.3)

8(8.0)

15(5.6)

0.366

NRDS (3–4)

206(20.9)

103(18.4)

18(18)

45(18.0)

0.370

BPDa

95/827(11.5)

47/455(10.3)

14/85(16.5)

21/202(10.4)

0.409

Death or BPD

75(14.7)

75(13.4)

16(16.0)

44(16.3)

0.694

SNI

15(1.5)

13(2.3)

0(0)

5(1.9)

0.361

Death or SNI

64(6.5)

39(7.0)

2(2.0)

27(10.0)

0.045

NEC

21(2.1)

12(2.1)

2(2.0)

9(3.3)

0.678

Death or NEC

73(7.4)

38(6.8)

3(3.0)

30(11.1)

0.038

ROPb

42(6.1)

14(3.4)

5(6.5)

7(3.9)

0.178

Death or ROP

95(9.6)

43(7.7)

7(7.0)

31(11.5)

0.258

EUGR

424(46.2)

266(51.8)

48(49.5)

99(41.8)

0.054

Head circumference at discharge

31(30,32)

31(30,32)

31(30,32)

31(30,32.5)

0.103

Length at discharge

44(43,46)

44(42.5,46)

44(43,45)

44.5(42,46)

0.461

Weight at discharge

2100(1970,2780)

2077(1930,2257.5)

2100(1960,2300)

2100(1955,2340)

0.174

Death

53(5.4)

29(5.2)

2(2.0)

24(8.9)

0.042

  1. Abbreviations: DR, delivery room; PS, Pulmonary Surfactant; ANS, Antenatal corticosteroids; NRDS, neonatal respiratory distress syndrome;EOS, early-onset sepsis; BPD, bronchopulmonary dysplasia; IVH, intraventricular hemorrhage; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity
  2. aBPD among survivors at 28 days
  3. bROP among infants conducted eye fundus examination