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Table 4 Comparison of mental health outcomes at 6 months postpartum

From: Do glycaemic treatment targets affect the perinatal mental health status of women with gestational diabetes? – Data from the TARGET Trial

Outcome

Tight glycemic targets

Less-tight glycemic targets

Relative risk or mean difference (95% CI)

N

n (%) or mean ± SD

N

n (%) or mean ± SD

Unadjusted

p-value

Adjustedb

p-value

Poor mental health compositea

156

34 (21.8)

169

33 (19.5)

1.11 (0.63, 1.94)

0.72

1.03 (0.58, 1.81)

0.93

Anxiety (STAI > 15)

161

22 (13.7)

172

20 (11.6)

1.34 (0.67, 2.69)

0.41

1.21 (0.59, 2.48)

0.61

STAI score

161

10.0 ± 3.4

172

10.3 ± 3.5

-0.04 (-0.90, 0.81)

0.92

-0.05 (-0.86, 0.76)

0.90

Depression (EPDS > 12)

162

15 (9.3)

170

10 (5.9)

1.54 (0.62, 3.87)

0.36

1.41 (0.53, 3.79)

0.50

EPDS score

162

5.4 ± 4.9

170

5.3 ± 4.3

0.43 (-0.73, 1.58)

0.47

0.47 (-0.52, 1.45)

0.35

Poor mental HRQoL (MCS < 40)

159

28 (17.9)

171

26 (15.2)

1.22 (0.66, 2.28)

0.52

1.11 (0.59, 2.08)

0.75

SF-36 scores:

 General health

164

72.6 ± 19.4

172

73.8 ± 17.7

-0.98 (-5.61, 3.66)

0.68

-0.48 (-4.71, 3.76)

0.83

 Mental health

165

72.3 ± 12.3

172

70.6 ± 12.1

0.57 (-2.56, 3.70)

0.72

-0.25 (-3.08, 2.58)

0.86

 Physical functioning

164

83.4 ± 23.4

172

89.1 ± 18.5

-3.84 (-9.18, 1.50)

0.16

-3.20 (-8.44, 2.05)

0.23

 Social functioning

166

85.4 ± 21.4

172

85.5 ± 19.4

0.13 (-4.98, 5.24)

0.96

1.89 (-2.98, 6.76)

0.45

 Role physical

164

83.7 ± 31.8

171

90.5 ± 22.6

-5.93 (-13.03, 1.17)

0.10

-2.29 (-9.18, 4.61)

0.52

 Role emotional

164

84.6 ± 32.9

171

89.7 ± 25.9

-5.49 (-12.94, 1.96)

0.15

-2.42 (-9.77, 4.92)

0.52

 Bodily pain

166

76.1 ± 21.5

172

78.6 ± 22.2

-2.34 (-7.80, 3.13)

0.40

-0.51 (-5.86, 4.84)

0.85

 Vitality

165

58.9 ± 15.5

172

57.4 ± 14.7

1.12 (-2.95, 5.19)

0.59

0.06 (-3.17, 3.30)

0.97

 PCS

159

51.0 ± 8.6

171

53.4 ± 7.4

-1.40 (-3.44, 0.65)

0.18

-0.83 (-2.84, 1.19)

0.42

 MCS

159

48.3 ± 9.2

171

47.2 ± 7.6

0.60 (-1.52, 2.72)

0.58

0.44 (-1.60, 2.48)

0.67

  1. aAny of anxiety (STAI > 15), vulnerability to depression (EPDS > 12) or poor mental health-related quality of life (SF-36 MCS < 40)
  2. bAdjusted for body mass index, gestational age at oral glucose tolerance test, ethnicity, and history of gestational diabetes
  3. CI confidence interval, EPDS Edinburgh Postnatal Depression Scale, HRQoL health-related quality of life, MCS Mental Component Summary, PCS Physical Component Summary, RR Relative risk, STAI Spielberger State-Trait Anxiety Inventory, SD standard deviation, SF-36 36-Item Short-Form General Health Survey