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Table 2 Diagnosis and delivery characteristics of twin pregnancies

From: Epidemiology and factors associated with preterm births in multiple pregnancy: a retrospective cohort study

Characteristic

Monochorionic twins (N = 241)

Dichorionic twins (N = 172)

Adjusted OR (95% CI)

P-value

Structural abnormality – n (%)

19 (7.9)

3 (1.7)

5.55 (1.54, 19.95)

0.009

Chromosome abnormality – n (%)

0

1

NA

 

In vitro fertilization conception– n (%)

11 (4.6)

58 (33.7)

0.12 (0.06, 0.25)

< 0.001

Mean gestational age at delivery

34.13 (4.10)

35.72 (2.61)

0.87 (0.81, 0.93)

< 0.001

 • < 28 weeks

21 (8.7)

04 (2.3)

  

 • 28 – < 34 weeks

57 (23.7)

24 (14.0)

  

 • 34—< 37 weeks

95 (39.4)

68 (39.5)

  

 • ≥ 37 weeks

68 (28.2)

76 (44.2)

  

Preterm birth

173 (71.8)

96 (55.8)

2.04 (1.32, 3.14)

0.001

 • Spontaneous preterm birth – n (%)

126 (52.3)

75 (43.6)

  

 • Induced preterm birth – n (%)

47 (19.5)

21 (12.2)

  

Preterm labor with inhibition

93 (38.6)

59 (34.3)

0.93 (0.67, 1.31)

0.693

 • Failed – n (%)

82 (88.2)

44 (74.6)

  

 • Successful – n (%)

11 (11.8)

15 (25.4)

  

Preterm PROM

41 (17.3)

35 (20.5)

0.80 (0.47, 1.35)

0.401

Dexamethasone

   

0.624

 • Partial (≤ 3 dose) – n (%)

19 (7.9)

10 (5.9)

1.34 (0.57, 3.16)

 

 • Complete – n (%)

76 (31.7)

46 (27.1)

1.28 (0.80, 2.03)

 

 • Rescue course – n (%)

8 (3.3)

3 (1.8)

1.76 (0.44, 6.95)

 

Mode of delivery

   

0.092

 • Previous CS – n (%)

32 (13.3)

19 (11.1)

1

 

 • Primary CS – n (%)

182 (75.5)

145 (84.3)

0.58 (0.29, 1.14)

 

 • Vaginal delivery and CS in second twin – n (%)

2 (0.81)

0 (0.00)

NA

 

 • Vaginal delivery – n (%)

25 (10.4)

8 (4.7)

1.21 (0.43, 3.42)

 

Indication for cesarean section

   

0.271

 • Multiple pregnancy – n (%)

110 (47.3)

83 (50.6)

0.56 (0.24, 1.31)

 

 • Abnormal presentation in first twin – n (%)

44 (18.3)

43 (25.0)

0.45 (0.18, 1.12)

 

 • Non-reassuring fetal status – n (%)

19 (7.9)

8 (4.7)

1.06 (0.32, 3.45)

 

 • Failed induction – n (%)

5 (2.1)

1 (0.6)

2.07 (0.20, 21.61)

 

 • Antepartum hemorrhage – n (%)

3 (1.2)

6 (3.5)

0.41 (0.08, 2.20)

 

 • Preeclampsia – n (%)

2 (0.8)

3 (1.7)

0.36 (0.05, 2.63)

 

 • Prolapsed cord – n (%)

1 (0.41)

0 (0.00)

NA

 
  1. CS cesarean section, antepartum hemorrhage; placenta previa, placental abruption and placenta accreta. Adjusted by age, parity, pre-pregnancy BMI and underlying medical conditions