Table 1 Main characteristics of the eligible studies included in the meta-analysis
Study | Year | Type of study | Country | Total cerclages (Mersiline tape/other) | Main outcomes | Cervical length at screening | The gestation weeks of cerclage place | Gestational weeks at delivery (wk + d) | Cerclage indication | Type of cerclage | Type of suture |
|---|---|---|---|---|---|---|---|---|---|---|---|
Lindsay M. Kindinger1 | 2016 | retrosp. Cohort | UK | 98(38/60) | Preterm birth rate | different length at different screening timepoint | NG | 37.3 ± 3.4/38.4 ± 2.8 | ultrasound-indicated | NG | Mersilen tape VS monofilament |
Lindsay M. Kindinger2 | 2016 | RCT | UK | 49(25/24) | vaginal microbial dysbiosis, inflammation, and pregnancy outcomes | 19 ± 4.5/18 ± 5.1 | 18 + 1 ± 3/17 + 6 ± 2.8 | NG | ultrasound-indicated and history-indicated | NG | Mersilene tape VS monofilament |
Vincenzo Berghella | 2012 | RCT | USA | 130(46/84) | preterm birth rate | 20.7/21 | 19.7 ± 2/19.6 ± 1.9 | 37.9/36.9 | ultrasound-indicated | McDonald cerclage | Mersilene tape VS Mersilene thread and Ethibond |
Ashley N. Battarbee | 2019 | retrosp. Cohort | USA | 203(120/83) | gestational age at delivery. preterm birth less than 34 weeks, chorioamnionitis, neonatal intensive care unit admission and composite neonatal morbidity | 16/11.5 | 14.3/15.9 | 37.2/36 | ultrasound-indicated and history-indicated and physical exam | McDonald, Shirodkar, or cervicoisthmic | Mersilene tape VS Ethibond and Prolene |
Victoria Hodgetts Morton | 2022 | RCT | UK | 1845(919/926) | pregnancy loss, maternal and pregnancy outcomes | 23.1/23.2 | 16.6/16.5 | 37.2/37.2 | ultrasound-indicated and history-indicated | NG | Mersilene tape VS Ethilon |