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Table 1 Pregnancy characteristics of women with two screening tests

From: A new contingent screening strategy increased detection rate of trisomy 21 in the first trimester

Characteristic

Serum biochemical screening

Combined first-trimester screening

P

Number

35,308

35,026

 

Age distribution

   

Maternal age at expected date of delivery < 35 years(%)

34,724(98.35%)

34,467(98.40%)

0.543

Maternal age at expected date of delivery ≥ 35 years(%)

584(1.65%)

559(1.60%)

0.543

Maternal age (years) at expected date of delivery (IQR)

30.00(28.06–32.13)

30.02(27.52–31.62)

0.215

Method of conception (%)

   

Spontaneous

33,118(93.80%)

32,798(93.64%)

0.387

Assisted

2,190(6.20%)

2,228(6.36%)

0.387

Median maternal weight (IQR)

53(49–58)

53(49–58)

0.896

Median gestational age (days) at blood sample (IQR)

88(85–92)

88(85–92)

0.605

Insulin-dependent diabetes (%)

24(0.07%)

24 (0.07%)

0.978

Smoker (%)

362(1.03%)

356(1.02%)

0.907

Incidence of Down syndrome(‰)

47(1.33‰,1/751)

47(1.34‰,1/745)

0.969

  1. *Data are given as median (interquartile range) or n (%). IQR, interquartile range