Table 2 Comparison of the outcome of COH in terms of oocytes and embryos among the three protocols
Protocols | GnRH agonist (n = 2116) | GnRH antagonist (n = 1628) | Mild stimulation (n = 512) | P value |
|---|---|---|---|---|
Starting dosage of Gn used (IU) | 262.41 ± 73.55 | 223.85 ± 62.52# | 115.83 ± 58.29#* | < 0.001 |
Total dosage of Gn used (IU) | 3952.59 ± 385.13 | 3251.85 ± 317.89# | 2696.25 ± 291.81#* | < 0.001 |
Duration of Gn used (days) | 14.04 ± 3.02 | 11.25 ± 2.96# | 12.53 ± 2.74# | 0.143 |
Oocyte number | 4.02 ± 2.25 | 3.15 ± 1.52# | 2.40 ± 1.26#* | < 0.001 |
MII number | 3.25 ± 2.59 | 2.60 ± 1.84# | 1.93 ± 1.03#* | < 0.001 |
Oocyte maturation rates (%) | 80.84 ± 14.36 | 81.51 ± 19.85 | 80.46 ± 15.93 | 0.931 |
Transferable embryos | 1.73 ± 1.02 | 1.35 ± 1.22# | 1.10 ± 0.86# | 0.016 |
Good-quality embryos | 1.51 ± 0.97 | 1.04 ± 0.89# | 0.97 ± 0.68# | 0.042 |
Fertilization rates (%) | 63.41 ± 32.52 | 59.43 ± 31.53 | 60.62 ± 36.11 | 0.825 |
OHSS rates | 4.63(98/2116) | 3.99(65/1628) | 2.15(11/512)# | 0.038 |