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Table 1 Comparison of baseline parameters among the three protocols

From: Analysis of controlled ovarian hyperstimulation protocols in women over 35 years old with poor ovarian response: a real-world study

Protocols

GnRH agonist

(n = 2116)

GnRH antagonist (n = 1628)

Mild stimulation

(n = 512)

P value

Age (years)

39.25 ± 3.05

38.98 ± 2.79

39.71 ± 3.62

0.581

Infertility years (years)

3.61 ± 2.46

3.46 ± 2.52

3.41 ± 2.23

0.285

Sterility type (%)

 Primary infertility

60.1(1272/2116)

59.8(973/1628)

58.0(297/512)

0.683

 Secondary infertility

39.9(844/2116)

40.2(655/1628)

42.0(215/512)

 

BMI (kg/m2)

25.21 ± 2.94

25.25 ± 3.52

25.81 ± 2.95

0.456

Basal FSH (IU/L)

9.66 ± 4.92

10.76 ± 5.32

10.25 ± 5.71

0.253

Basal LH (IU/L)

4.52 ± 2.24

4.84 ± 2.31

4.41 ± 2.25

0.352

Basal E2 (ng/L)

46.81 ± 32.04

44.95 ± 36.5

43.49 ± 30.75

0.795

Basal P (µg/L)

0.57 ± 0.51

0.49 ± 0.31

0.58 ± 0.42

0.305

AMH (ng/mL)

0.67 ± 0.21

0.75 ± 0.31

0.61 ± 0.31

0.152

TSH (mlU/ml)

2.33 ± 1.14

2.42 ± 1.25

2.61 ± 1.54

0.621

FT3 (pmol/L)

5.41 ± 0.91

5.41 ± 0.65

5.56 ± 0.67

0.964

FT4 (pmol/L)

11.34 ± 2.71

12.01 ± 1.99

11.56 ± 2.05

0.520

Method of fertilization

IVF

76.9(1627/2116)

73.9(1203/1628)

76.4(391/512)

0.098

ICSI

23.1(489/2116)

26.1(425/1628)

23.6(121/512)

 
  1. BMI, body mass index; FSH, follicular-stimulating hormone; LH, luteinizing hormone; E2, estradiol; P, progesterone; AMH, anti-Müllerian hormone;TSH, thyroid stimulating hormone; FT3, serum free triiodothyronine; FT4, Serum free thyroxine
  2. #P < 0.05, vs. GnRH agonist; *P < 0.05, vs. GnRH antagonist