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Table 4 Baseline characteristics and pregnancy outcomes of patients with different stages of blastocysts transferred in two groups (\(\bar x\) ± s; %)

From: Stratified analysis of clinical pregnancy outcomes of sequential embryo transfer in frozen embryo transfer cycles based on different factors: a retrospective study

Indicators

D5 blastocyst transferred

D6 blastocyst transferred

Conventional ET

(n = 208)

Sequential ET

(n = 216)

P-value

Conventional ET

(n = 148)

Sequential ET

(n = 144)

P-value

Age (yr)

31.78 ± 4.58

31.76 ± 4.52

0.968

31.40 ± 3.95

31.69 ± 4.41

0.596

BMI (kg/m2)

22.74 ± 3.34

22.77 ± 3.75

0.935

22.48 ± 3.10

22.34 ± 3.19

0.737

Infertility duration (yr)

3.74 ± 2.72

3.78 ± 2.85

0.877

3.44 ± 2.59

3.69 ± 2.70

0.452

AMH (ng/ml)

5.38 ± 4.64

5.70 ± 4.90

0.501

5.75 ± 4.35

5.76 ± 4.78

0.984

bFSH (mIU/ml)

6.82 ± 2.45

6.81 ± 4.13

0.977

6.55 ± 2.10

6.52 ± 3.00

0.926

Number of failed cycles

2.97 ± 1.76

3.16 ± 1.64

0.265

3.28 ± 1.53

3.33 ± 1.77

0.112

Endometrial thickness (mm)

10.94 ± 1.92

10.74 ± 2.08

0.319

10.92 ± 2.06

11.06 ± 2.26

0.718

High-quality embryos rate

41.3 (172/416)

45.1 (223/494)

0.250

37.7 (86/228)

42.5 (141/332)

0.261

Primary infertility rate

51.9 (108/208)

59.7 (129/216)

0.106

58.8 (87/148)

56.9 (82/144)

0.750

Infertility factors

      

Male factors

22.1 (46/208)

24.5 (53/216)

0.556

27.0 (40/148)

22.9 (33/144)

0.417

Tube and pelvic factors

42.3 (88/208)

43.1 (93/216)

0.876

41.9 (62/148)

37.5 (54/144)

0.443

Ovulatory factors

3.8 (8/208)

5.6 (12/216)

0.407

3.4 (5/148)

4.2 (6/144)

0.724

Couples’ factors

18.3 (38/208)

19.0 (41/216)

0.851

20.3 (30/148)

24.3 (35/144)

0.407

Others

13.5 (28/208)

7.9 (17/216)

0.062

7.4 (11/148)

11.1 (16/144)

0.278

Clinical pregnancy rate

24.5 (51/208)

33.8 (73/216)

0.036*

17.6 (26/148)

28.5 (41/144)

0.027*

Implantation rate

17.0 (60/416)

19.6 (97/494)

0.038*

10.1 (30/296)

15.4 (51/332)

0.051

Multiple pregnancy rate

17.6 (9/51)

24.7 (18/73)

0.352

15.4 (4/26)

19.5 (8/41)

0.668

Miscarriage rate

11.8 (6/51)

12.3 (9/73)

0.924

15.4 (4/26)

14.6 (6/41)

0.933

  1. Note: BMI = Body mass index; AMH = anti-Mullerian hormone; bFSH = base follicle stimulating hormone. *P < 0.05