Table 3 TheriskofSApatients with normal and abnormal foetal tissue chromosome karyotypes by age in allregions

All

 < 35

886

1484

10.6

 < 0.001

59.7

(57.2–62.2)

Ref

(1.1–1.5)

Ref

(6.4–10.3)

 ≥ 35

286

419

68.3

(63.6–72.5)

1.3

8.6

East

 < 35

219

353

5.6

0.018

62

(57.0–67.1)

Ref

(1.1–1.5)

Ref

(3.0–27.1)

 ≥ 35

41

52

78.8

(67.7–89.9)

1.3

16.8

North

 < 35

48

78

1.8

0.187

61.5

(50.7–72.3)

Ref

(0.9–1.6)

Ref

(-7.4–31.2)

 ≥ 35

19

25

76

(59.3–92.7)

1.2

14.5

Northwest

 < 35

109

233

4.8

0.029

46.8

(40.4–53.2)

Ref

(1.1–1.7)

Ref

(1.7–28.8)

 ≥ 35

37

59

62.7

(50.4–75.1)

1.3

15.9

South

 < 35

125

291

6.5

0.011

43.0

(37.4–48.7)

Ref

(1.1–1.6)

Ref

(10.4–15.3)

 ≥ 35

79

141

56.0

(47.8–64.0)

1.3

13.0

Southwest

 < 35

385

547

4.5

0.038

71.2

(67.2–74.8)

Ref

(0.9–1.7)

Ref

(0.9–7.9)

 ≥ 35

99

124

76.2

(68.1–82.7)

1.2

5.0