From: Identification and validation of diagnostic biomarkers for intrahepatic cholestasis of pregnancy based on untargeted and targeted metabolomics analyses of urine metabolite profiles
Biomarker
Cutoff value (ng/mL)
Diagnostic sensitivity
Diagnostic specificity
Youden index
AUC
3-hydroxypropionic acid
19681.936
0.800
0.900
0.7
0.920
28799.566
uracil
2938.360
0.700
0.6
0.850
3271.682
1.000
0.600