Table 4 Hit compounds in five remarkably enriched pathways
Pathway | Total | Hit | P value | Impact | Hit compound |
|---|---|---|---|---|---|
Beta-Alanine metabolism | 21 | 4 | 0.00283 | 0.0560 | 3-Hydroxypropionic acid; 5,6-Dihydrouracil; Uracil; L-Histidine |
Histidine metabolism | 16 | 3 | 0.0105 | 0.2213 | Â L-Glutamate; L-Histidine; Imidazole-4-acetate |
D-Glutamine and D-glutamate metabolism | 6 | 2 | 0.0120 | 0.5000 | Â L-Glutamate; D-Glutamine |
Primary bile acid biosynthesis | 46 | 4 | 0.0446 | 0.0259 | Cholic acid; Glycochenodeoxycholate; Glycocholate; Taurocholate |
Steroid hormone biosynthesis | 85 | 5 | 0.1030 | 0.2615 | 17-alpha-Hydroxyprogesterone; Testosterone; Androstenedione; Androsterone; 16-Glucuronide-estriol |